Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 5/20 | 0.39 |
| ▸ | FTO | Q9C0B1 | 4/20 | 0.39 |
| ▸ | BBOX1 | O75936 | 3/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | FLT1 | P17948 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5141913 | 0.91 | ABCG2 (0.41) | KDM4EMEN1KMT2AMAPTEGLN1 | |
| SCHEMBL522232 | 0.80 | EGLN1 (0.66) | KDM4EMEN1CRHBPKMT2ACRHR2 | |
| SCHEMBL523578 | 0.80 | EGLN1 (0.66) | KDM4EMEN1CRHBPKMT2ACRHR2 | |
| SCHEMBL522233 | 0.80 | EGLN1 (0.66) | KDM4EMEN1CRHBPKMT2ACRHR2 | |
| SCHEMBL5934945 | 0.78 | EGLN1 (0.43) | EGLN1FTOBBOX1 | |
| SCHEMBL30274512 | 0.77 | EGLN1 (0.66) | KDM4EEGLN1FTOBBOX1 | |
| SCHEMBL4755914 | 0.76 | EGLN1 (0.65) | KDM4EEGLN1FTOBBOX1 | |
| SCHEMBL1076121 | 0.73 | EGLN1 (0.43) | MAPTTP53EGLN1FTOBBOX1 | |
| SCHEMBL2354419 | 0.69 | THRB (0.43) | EGLN1FTOBBOX1 | |
| SCHEMBL521900 | 0.67 | EGLN1 (0.66) | EGLN1FTOBBOX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116018136-A | Hypoxia-inducible factor prolyl hydroxylase inhibitors for the treatment of aging-related disorders | 百爱及生物医药公司 | 2023-04-25 | — | — | CN | disclosed |
| WO-2006099610-A2 | METHODS OF IDENTIFYING THERAPEUTIC TARGETS FOR THE TREATMENT OF VULVOVAGINAL ATROPHY | WYETH (US) | 2006-09-21 | — | — | WO | disclosed |