Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 9/20 | 0.57 |
| ▸ | DRD3 | P35462 | 6/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.56 |
| ▸ | DRD4 | P21917 | 3/20 | 0.55 |
| ▸ | FAAH | O00519 | 1/20 | 0.55 |
| ▸ | CNR1 | P21554 | 1/20 | 0.55 |
| ▸ | BCHE | P06276 | 1/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5809389 | 0.91 | BCHE (0.66) | DRD2DRD3ADRA1ADRD4BCHE | |
| Hydrochloric Acid SCHEMBL5805712 | 0.90 | BCHE (0.64) | DRD2DRD3ADRA1ADRD4FAAH | |
| SCHEMBL5820335 | 0.85 | DRD2 (0.59) | DRD2DRD3ADRA1ADRD4FAAH | |
| Hydrochloric Acid SCHEMBL5819947 | 0.84 | DRD2 (0.58) | DRD2DRD3ADRA1ADRD4FAAH | |
| SCHEMBL5816386 | 0.81 | DRD2 (0.56) | DRD2DRD3ADRA1A | |
| SCHEMBL8980577 | 0.77 | DRD2 (0.75) | DRD2DRD3DRD4SLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL5809774 | 0.77 | DRD2 (0.65) | DRD2DRD3ADRA1ADRD4FAAH | |
| SCHEMBL3162960 | 0.77 | DRD2 (0.76) | DRD2DRD3DRD4FAAHSLC6A2 | |
| SCHEMBL5457389 | 0.74 | DRD2 (0.73) | DRD2DRD3ADRA1ADRD4SLC6A2 | |
| SCHEMBL14761584 | 0.74 | DRD2 (0.94) | DRD2DRD3ADRA1ADRD4SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006117760-A1 | ADRENERGIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2006-11-09 | — | — | WO | disclosed |