Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 3/20 | 0.47 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.47 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.47 |
| ▸ | TNKS | O95271 | 2/20 | 0.31 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2387462 | 0.97 | RXRA (0.48) | RXRANR1H2NR1H3TNKSTNKS2 | |
| SCHEMBL2386965 | 0.95 | RXRA (0.52) | RXRANR1H2NR1H3 | |
| SCHEMBL2390406 | 0.90 | RXRA (0.51) | RXRANR1H2NR1H3 | |
| SCHEMBL2386482 | 0.89 | RXRA (0.50) | RXRANR1H2NR1H3 | |
| SCHEMBL2386341 | 0.88 | RXRA (0.58) | RXRANR1H2NR1H3TNKSTNKS2 | |
| SCHEMBL2387524 | 0.88 | RXRA (0.57) | RXRANR1H2NR1H3TNKSTNKS2 | |
| SCHEMBL2389329 | 0.86 | RXRA (0.52) | RXRANR1H2NR1H3 | |
| SCHEMBL2386410 | 0.86 | RXRA (0.53) | RXRANR1H2NR1H3TNKSTNKS2 | |
| SCHEMBL2390404 | 0.86 | RXRA (0.51) | RXRANR1H2NR1H3 | |
| SCHEMBL2387198 | 0.85 | RXRA (0.63) | RXRANR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006025979-A9 | MODULATORS OF NUCLEAR RECEPTORS | EXELIXIS INC (US) | 2006-04-20 | — | — | WO | disclosed |