Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.74 |
| ▸ | MEN1 | O00255 | 6/20 | 0.74 |
| ▸ | TGM2 | P21980 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 3/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | NAMPT | P43490 | 1/20 | 0.61 |
| ▸ | MITF | O75030 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | MYOC | Q99972 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1177730 | 0.85 | MEN1 (1.00) | KMT2AMEN1TGM2NPC1RAB9A | |
| SCHEMBL6302157 | 0.85 | MEN1 (1.00) | KMT2AMEN1TGM2NPC1RAB9A | |
| SCHEMBL152811 | 0.83 | KMT2A (0.74) | KMT2AMEN1TGM2NPC1RAB9A | |
| SCHEMBL477790 | 0.82 | KMT2A (0.71) | KMT2AMEN1TGM2NPC1RAB9A | |
| SCHEMBL1102071 | 0.82 | KMT2A (0.71) | KMT2AMEN1TGM2NPC1RAB9A | |
| SCHEMBL6631700 | 0.82 | KMT2A (0.71) | KMT2AMEN1TGM2NPC1RAB9A | |
| SCHEMBL8848976 | 0.82 | KMT2A (0.71) | KMT2AMEN1TGM2NPC1RAB9A | |
| SCHEMBL642700 | 0.82 | KMT2A (0.81) | KMT2AMEN1NPC1MAPTMAPK1 | |
| SCHEMBL4588400 | 0.82 | KMT2A (0.71) | KMT2AMEN1TGM2NPC1RAB9A | |
| SCHEMBL9018657 | 0.82 | MEN1 (0.71) | KMT2AMEN1TGM2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006138589-A2 | OPIOID RECEPTOR LIGANDS | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2006-12-28 | — | — | WO | claimed |
| EP-0239528-A1 | 13-Beta-carbamoyloxy-milbemicyne derivatives for fighting harmful animal and plant parasites | CIBA-GEIGY AG (CH) | 1987-09-30 | — | — | EP | disclosed |
| US-4191574-A | AZO-METHINE DYES | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1980-03-04 | — | — | US | disclosed |
| US-4138264-A | Silver halide emulsion containing two equivalent type coupler for use in photography | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1979-02-06 | — | — | US | disclosed |