SCHEMBL152811

SCHEMBL152811

O=C(O)Nc1ccc([N+](=O)[O-])cc1

nearest known ligand 0.74

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 8/20 0.74
▸ MEN1 O00255 7/20 0.74
▸ NPC1 O15118 3/20 0.66
▸ RAB9A P51151 2/20 0.66
▸ POLB P06746 2/20 0.66
▸ MITF O75030 1/20 0.66
▸ TGM2 P21980 1/20 0.62
▸ MAPT P10636 3/20 0.61
▸ MAPK1 P28482 2/20 0.61
▸ GAA P10253 2/20 0.61
▸ NAMPT P43490 1/20 0.61
▸ NPSR1 Q6W5P4 1/20 0.61
▸ MYOC Q99972 1/20 0.61
▸ SMN1; SMN2 Q16637 2/20 0.59
▸ LMNA P02545 1/20 0.59
▸ ALDH1A1 P00352 2/20 0.58
▸ HPGD P15428 1/20 0.57
▸ ALOX12 P18054 1/20 0.57
▸ L3MBTL1 Q9Y468 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17289271 0.94 KMT2A (0.67) KMT2AMEN1NPC1RAB9APOLB
SCHEMBL4690573 0.89 MEN1 (0.79) KMT2AMEN1NPC1RAB9APOLB
Hydrochloric Acid SCHEMBL11555611 0.89 KMT2A (0.61) KMT2AMEN1NPC1RAB9APOLB
Nitrobenzene SCHEMBL28122132 0.88 MEN1 (0.62) KMT2AMEN1NPC1RAB9APOLB
SCHEMBL1177730 0.85 MEN1 (1.00) KMT2AMEN1NPC1RAB9APOLB
SCHEMBL6302157 0.85 MEN1 (1.00) KMT2AMEN1NPC1RAB9APOLB
SCHEMBL3189929 0.84 KMT2A (0.69) KMT2AMEN1NPC1RAB9APOLB
SCHEMBL5817153 0.83 KMT2A (0.74) KMT2AMEN1NPC1RAB9APOLB
SCHEMBL21597887 0.83 NAMPT (0.63) KMT2AMEN1NPC1RAB9APOLB
SCHEMBL11055960 0.82 MEN1 (0.85) KMT2AMEN1NPC1RAB9APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 551 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119931396-A Water-based asphalt insect-damage-prevention anticorrosive paint and processing technology thereof 安徽欣苗新材料科技有限公司 2025-05-06 — — CN claimed
EP-3407916-B1 PHOSPHONATE LINKERS AND THEIR USE TO FACILITATE CELLULAR RETENTION OF COMPOUNDS MERCK SHARP & DOHME LLC (US) 2023-12-20 — — EP claimed
CN-106771137-B Detect enzyme linked immunological kit and its application of Nicarbazin 浙江省食品药品检验研究院 2018-10-02 — — CN claimed
CN-106771137-A Detect enzyme linked immunological kit and its application of Nicarbazin 浙江省食品药品检验研究院 2017-05-31 — — CN claimed
US-9448173-B2 Dye-conjugated dendrimers THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2016-09-20 — — US claimed
EP-1718667-B1 HETEROCYCLIC SELF-IMMOLATIVE LINKERS AND CONJUGATES GENENTECH INC (US) 2013-01-09 — — EP claimed
US-20120256102-A1 Dye-conjugated dendrimers THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2012-10-11 — — US claimed
WO-2006138589-A2 OPIOID RECEPTOR LIGANDS UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) 2006-12-28 — — WO claimed
US-20040110768-A1 Bombesin receptor antagonists WARNER-LAMBERT COMPANY LLC 2004-06-10 — — US claimed
US-5378836-A Antibody inhibitors, fungicides; antiinflammatory and antitumor agents AMERICAN HOME PRODUCTS CORPORATION (US) 1995-01-03 — — US claimed
EP-0509795-A2 Carbamates of rapamycin AMERICAN HOME PRODUCTS CORPORATION (US) 1992-10-21 — — EP claimed
US-5118678-A Antibody inhibitors, antiinflammatory agents, fungicides, antitumor agents AMERICAN HOME PRODUCTS CORPORATION (US) 1992-06-02 — — US claimed
EP-4698275-A1 PYRROLIDINONE UREA FPR2 AGONISTS Bristol-Myers Squibb Company (US) 2026-02-25 — — EP disclosed
EP-4698516-A1 PYRROLIDINONE UREA FPR2 AGONISTS Bristol-Myers Squibb Company (US) 2026-02-25 — — EP disclosed
US-20250296971-A1 GASTRIC INHIBITORY PEPTIDE RECEPTOR LIGANDS 3B PHARMACEUTICALS GMBH (DE) 2025-09-25 — — US disclosed
EP-4610269-A1 UROKINASE PLASMINOGEN ACTIVATOR SURFACE RECEPTOR (UPAR) LIGANDS FOR DIAGNOSTIC OR THERAPEUTIC USE 3B Pharmaceuticals GmbH (DE) 2025-09-03 — — EP disclosed
US-4170708-A FROM AN AROMATIC NITRO COMPOUND, AN ALCOHOL, AND CARBON MONOXIDE MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1979-10-09 — — US disclosed
US-4138264-A Silver halide emulsion containing two equivalent type coupler for use in photography KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1979-02-06 — — US disclosed
US-4134880-A Process for producing an aromatic urethane from nitro compounds, hydroxyl compounds and carbon monoxide using metal-Lewis acid-ammonia catalyst systems MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1979-01-16 — — US disclosed
US-4061630-A 7-Substituted-ureido-3-carbamoyloxymethyl cephalosporin antibiotics ELI LILLY AND COMPANY (US) 1977-12-06 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250296971-A1 GASTRIC INHIBITORY PEPTIDE RECEPTOR LIGANDS GIPR, VIP, GRPR KMT2A 3863/4885MEN1 1139/4885NPC1 4323/4885
US-20040110768-A1 Bombesin receptor antagonists NPY1R, BDKRB1, NPY2R KMT2A 3281/4885MEN1 343/4885NPC1 2690/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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