Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | KYAT1 | Q16773 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5817856 | 1.00 | ABCB1 (0.60) | ABCB1MAPTKMT2AMEN1L3MBTL1 | |
| SCHEMBL4404099 | 0.87 | ABCB1 (0.52) | ABCB1MAPTKMT2AMEN1L3MBTL1 | |
| SCHEMBL14139923 | 0.87 | ABCB1 (0.52) | ABCB1MAPTKMT2AMEN1L3MBTL1 | |
| SCHEMBL502387 | 0.85 | ABCB1 (0.53) | ABCB1MAPTKMT2AMEN1L3MBTL1 | |
| SCHEMBL502388 | 0.85 | ABCB1 (0.53) | ABCB1MAPTKMT2AMEN1L3MBTL1 | |
| SCHEMBL10056749 | 0.85 | ABCB1 (0.53) | ABCB1MAPTKMT2AMEN1L3MBTL1 | |
| SCHEMBL7826269 | 0.85 | MAPT (0.50) | MAPTKMT2AL3MBTL1KDM4EGAA | |
| SCHEMBL6161702 | 0.84 | MAPT (0.52) | ABCB1MAPTKMT2AMEN1L3MBTL1 | |
| SCHEMBL1491860 | 0.84 | MEN1 (0.61) | ABCB1MAPTKMT2AMEN1KDM4E | |
| SCHEMBL1491858 | 0.84 | MEN1 (0.61) | ABCB1MAPTKMT2AMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006030285-A1 | NEW 1,2,4-TRIAZOLE-3-CARBOXAMIDE DERIVATIVES | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2006-03-23 | — | — | WO | disclosed |