Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30720830 | 0.86 | MAPT (0.58) | MAPTALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL13875566 | 0.86 | MAPT (0.58) | MAPTALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL10836433 | 0.80 | MAPT (0.45) | MAPTALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL10836424 | 0.80 | MAPT (0.45) | MAPTALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL28382652 | 0.76 | NPC1 (0.46) | MAPTALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL28382648 | 0.76 | NPC1 (0.46) | MAPTALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL7494202 | 0.76 | GAA (0.49) | MAPTALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL10631063 | 0.76 | HPGD (0.72) | MAPTALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL31757610 | 0.75 | KDM4E (0.51) | MAPTALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL31757608 | 0.75 | KDM4E (0.51) | MAPTALDH1A1MEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006030285-A1 | NEW 1,2,4-TRIAZOLE-3-CARBOXAMIDE DERIVATIVES | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2006-03-23 | — | — | WO | disclosed |