Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | KLK7 | P49862 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5813569 | 0.85 | ALDH1A1 (0.39) | ALDH1A1MAPTNPC1ALOX15RAB9A | |
| SCHEMBL3565837 | 0.79 | CNR1 (0.39) | ALDH1A1MAPTSMN1; SMN2NPSR1TSHR | |
| SCHEMBL5818284 | 0.79 | ALDH1A1 (0.35) | ALDH1A1MAPTNPC1ALOX15RAB9A | |
| SCHEMBL3569301 | 0.78 | CNR1 (0.39) | ALDH1A1MAPTNPC1GAAKMT2A | |
| SCHEMBL5818281 | 0.75 | MAPT (0.35) | ALDH1A1MAPTNPC1ALOX15RAB9A | |
| SCHEMBL3566275 | 0.71 | CNR2 (0.35) | ALDH1A1MAPTGAAMEN1KMT2A | |
| SCHEMBL5813565 | 0.69 | ALDH1A1 (0.39) | ALDH1A1MAPTNPC1ALOX15RAB9A | |
| SCHEMBL5819200 | 0.69 | ALDH1A1 (0.56) | ALDH1A1MAPTNPC1ALOX15RAB9A | |
| SCHEMBL5813659 | 0.67 | ALDH1A1 (0.37) | ALDH1A1MAPTNPC1ALOX15RAB9A | |
| SCHEMBL3563083 | 0.67 | CHRM2 (0.34) | ALDH1A1MEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006063113-A2 | UREAS AS FACTOR XA INHIBITORS | PORTOLA PHARMACEUTICALS, INC. (US) | 2006-06-15 | — | — | WO | disclosed |