Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.41 |
| ▸ | CDK1 | P06493 | 2/20 | 0.40 |
| ▸ | CDK4 | P11802 | 2/20 | 0.40 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.40 |
| ▸ | CCND1 | P24385 | 2/20 | 0.40 |
| ▸ | CDK2 | P24941 | 2/20 | 0.40 |
| ▸ | CCND3 | P30281 | 2/20 | 0.40 |
| ▸ | CDK7 | P50613 | 2/20 | 0.40 |
| ▸ | CCNH | P51946 | 2/20 | 0.40 |
| ▸ | CDK6 | Q00534 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5819074 | 0.99 | ALDH1A1 (0.47) | ALDH1A1ALOX5KMT2ADYRK1ADGAT1 | |
| SCHEMBL5813636 | 0.96 | ALDH1A1 (0.48) | ALDH1A1ALOX5KMT2ADYRK1ADGAT1 | |
| SCHEMBL5812813 | 0.92 | KCNH2 (0.47) | ALOX5DGAT1CDK1CDK4CCNB1 | |
| SCHEMBL5817854 | 0.91 | KCNH2 (0.48) | ALOX5DGAT1CDK1CDK4CCNB1 | |
| SCHEMBL5812944 | 0.88 | KCNH2 (0.47) | CDK2 | |
| SCHEMBL5815226 | 0.87 | KMT2A (0.50) | ALDH1A1ALOX5KMT2AHTTNPSR1 | |
| SCHEMBL5819436 | 0.87 | ALDH1A1 (0.43) | ALDH1A1ALOX5KMT2ADYRK1ADGAT1 | |
| SCHEMBL5818666 | 0.87 | MAPK14 (0.43) | ALOX5KMT2ADGAT1GPR119CDK1 | |
| SCHEMBL5818777 | 0.86 | KMT2A (0.60) | ALDH1A1KMT2ACDK1CDK4CCNB1 | |
| SCHEMBL5818376 | 0.86 | BRAF (0.46) | ALOX5DGAT1CDK1CDK4CCNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006137658-A1 | NEW SUBSTITUTED 1,3-THIAZOLE DERIVATIVES OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF HAVING IMMUNOSUPPRESSION AND INFLAMMATION INHIBITORY ACITIVITY, INTERMEDIATE COMPOUNDS OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, A PROCESS FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | DONGBU HITEK CO., LTD. (KR) | 2006-12-28 | — | — | WO | disclosed |