Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 14/20 | 0.52 |
| ▸ | CAMK2D | Q13557 | 3/20 | 0.44 |
| ▸ | MAPK13 | O15264 | 5/20 | 0.44 |
| ▸ | MAPK12 | P53778 | 5/20 | 0.44 |
| ▸ | MAPK11 | Q15759 | 5/20 | 0.44 |
| ▸ | IDH1 | O75874 | 1/20 | 0.42 |
| ▸ | PLK1 | P53350 | 1/20 | 0.42 |
| ▸ | BRAF | P15056 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5819565 | 1.00 | MAPK14 (0.52) | MAPK14CAMK2DMAPK13MAPK12MAPK11 | |
| SCHEMBL5813651 | 0.86 | CCNT1 (0.51) | MAPK14CAMK2DMAPK13MAPK12MAPK11 | |
| SCHEMBL5813647 | 0.86 | CCNT1 (0.51) | MAPK14CAMK2DMAPK13MAPK12MAPK11 | |
| SCHEMBL5819614 | 0.84 | MAPK14 (0.67) | MAPK14MAPK13MAPK12MAPK11PLK1 | |
| Hydrochloric Acid SCHEMBL1518816 | 0.83 | MAPK14 (0.66) | MAPK14MAPK13MAPK12MAPK11PLK1 | |
| SCHEMBL5812491 | 0.83 | CAMK2D (0.47) | MAPK14CAMK2DMAPK13MAPK12MAPK11 | |
| SCHEMBL5813688 | 0.81 | MAPK14 (0.53) | MAPK14CAMK2DMAPK13MAPK12MAPK11 | |
| SCHEMBL5820847 | 0.80 | MAPK13 (0.54) | MAPK14CAMK2DMAPK13MAPK12MAPK11 | |
| SCHEMBL5820631 | 0.80 | MAPK13 (0.55) | MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL5818665 | 0.80 | MAPK9 (0.59) | MAPK14MAPK13MAPK12MAPK11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006137658-A1 | NEW SUBSTITUTED 1,3-THIAZOLE DERIVATIVES OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF HAVING IMMUNOSUPPRESSION AND INFLAMMATION INHIBITORY ACITIVITY, INTERMEDIATE COMPOUNDS OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, A PROCESS FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | DONGBU HITEK CO., LTD. (KR) | 2006-12-28 | — | — | WO | claimed |
| WO-2006137658-A1 | NEW SUBSTITUTED 1,3-THIAZOLE DERIVATIVES OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF HAVING IMMUNOSUPPRESSION AND INFLAMMATION INHIBITORY ACITIVITY, INTERMEDIATE COMPOUNDS OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, A PROCESS FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | DONGBU HITEK CO., LTD. (KR) | 2006-12-28 | — | — | WO | disclosed |