Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 10/20 | 0.49 |
| ▸ | CDK4 | P11802 | 5/20 | 0.49 |
| ▸ | CCNE1 | P24864 | 4/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.44 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.43 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.43 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.43 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.43 |
| ▸ | PRKD2 | Q9BZL6 | 2/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | MATK | P42679 | 1/20 | 0.43 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.43 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.43 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.43 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.43 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.43 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.43 |
| ▸ | MAP3K20 | Q9NYL2 | 1/20 | 0.43 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5819642 | 0.85 | CDK2 (0.49) | CDK2CDK4CCNE1HDAC1CDK19 | |
| SCHEMBL415283 | 0.85 | CDK2 (0.49) | CDK2CDK4CCNE1HDAC1PRKD3 | |
| SCHEMBL414098 | 0.84 | CDK2 (0.48) | CDK2CDK4CCNE1HDAC1PRKD3 | |
| SCHEMBL409738 | 0.84 | HDAC1 (0.56) | CDK2CDK4CCNE1HDAC1 | |
| SCHEMBL412401 | 0.84 | CDK2 (0.56) | CDK2CDK4CCNE1HDAC1CDK19 | |
| SCHEMBL413670 | 0.83 | CDK19 (0.49) | CDK2CDK4CCNE1HDAC1CDK19 | |
| SCHEMBL412332 | 0.83 | DYRK3 (0.54) | CDK2CDK4CCNE1HDAC1PRKD3 | |
| SCHEMBL414114 | 0.83 | MAPK1 (0.53) | CDK2CDK4CCNE1HDAC1PRKD3 | |
| SCHEMBL3360699 | 0.83 | HDAC1 (0.54) | CDK2CDK4CCNE1HDAC1CDK19 | |
| SCHEMBL5138510 | 0.81 | CDK2 (0.53) | CDK2CDK4CCNE1HDAC1PRKD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546112-A4 | IMIDAZOLOPYRIDINES AND METHODS OF MAKING AND USING THE SAME | BIOGEN IDEC INC (US) | 2006-06-07 | — | — | EP | disclosed |
| EP-1546112-A2 | IMIDAZOLOPYRIDINES AND METHODS OF MAKING AND USING THE SAME | Biogen Idec MA Inc. (US) | 2005-06-29 | — | — | EP | disclosed |
| WO-2004021989-A2 | IMIDAZOLOPYRIDINES AND METHODS OF MAKING AND USING THE SAME | BIOGEN IDEC MA INC. (US) | 2004-03-18 | — | — | WO | disclosed |