Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR9 | Q9NR96 | 3/20 | 0.44 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.44 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 9/20 | 0.42 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.42 |
| ▸ | EZH1 | Q92800 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.41 |
| ▸ | RET | P07949 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1743020 | 0.80 | HDAC4 (0.40) | TLR9TLR8TLR7HRH3HDAC4 | |
| SCHEMBL12159751 | 0.79 | TLR9 (0.48) | TLR9TLR8TLR7HRH3HDAC4 | |
| SCHEMBL1742758 | 0.79 | TLR9 (0.52) | TLR9TLR8TLR7HRH3ACVR1 | |
| SCHEMBL1744089 | 0.79 | CNR2 (0.49) | TLR9TLR8TLR7HRH3ACVR1 | |
| SCHEMBL1742814 | 0.79 | HRH3 (0.52) | TLR9TLR8TLR7HRH3HDAC4 | |
| SCHEMBL15166541 | 0.77 | TLR9 (0.55) | TLR9TLR8TLR7HRH3HDAC4 | |
| SCHEMBL6616137 | 0.77 | MAPT (0.56) | HRH3HDAC4 | |
| SCHEMBL27903431 | 0.77 | TLR9 (0.43) | TLR9TLR8TLR7HRH3ACVR1 | |
| SCHEMBL1742225 | 0.77 | HRH3 (0.51) | HRH3 | |
| SCHEMBL1742769 | 0.76 | HRH3 (0.54) | TLR9TLR8TLR7HRH3ACVR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006120349-A1 | NOVEL PHENYL-PYRIDINYL-PIPERAZINE DERIVATIVES, A METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID DERIVATIVES | LES LABORATOIRES SERVIER (FR) | 2006-11-16 | — | — | WO | disclosed |