Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.34 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.34 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.34 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.34 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 7/20 | 0.32 |
| ▸ | CNR1 | P21554 | 6/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | CCR2 | P41597 | 2/20 | 0.31 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.31 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.30 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5819790 | 0.91 | S1PR1 (0.37) | THRATHRBS1PR1S1PR3S1PR2 | |
| SCHEMBL4433994 | 0.83 | THRA (0.48) | THRATHRBS1PR1S1PR3S1PR2 | |
| SCHEMBL4289276 | 0.83 | THRA (0.48) | THRATHRBS1PR1S1PR3S1PR2 | |
| SCHEMBL5795188 | 0.82 | S1PR1 (0.43) | THRATHRBS1PR1S1PR3S1PR2 | |
| SCHEMBL4287826 | 0.81 | S1PR2 (0.49) | THRATHRBS1PR1S1PR3S1PR2 | |
| SCHEMBL4294265 | 0.81 | S1PR2 (0.49) | THRATHRBS1PR1S1PR3S1PR2 | |
| SCHEMBL4289431 | 0.81 | S1PR2 (0.49) | THRATHRBS1PR1S1PR3S1PR2 | |
| SCHEMBL4294716 | 0.80 | S1PR1 (0.49) | THRATHRBS1PR1S1PR3S1PR2 | |
| SCHEMBL4289649 | 0.79 | S1PR1 (0.47) | S1PR1S1PR3S1PR2S1PR4S1PR5 | |
| SCHEMBL4293664 | 0.79 | S1PR1 (0.47) | S1PR1S1PR3S1PR2S1PR4S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006043149-A9 | NOVEL DICARBOXYLIC ACID DERIVATIVES | BIOPROJET SOC CIV (FR) | 2006-08-10 | — | — | WO | disclosed |