SCHEMBL5820002

SCHEMBL5820002

COc1ccc(NC(=O)c2cc3ccc4c5ccccc5[nH]c4c3cc2O)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 7/20 1.00
▸ KMT2A Q03164 7/20 1.00
▸ MAPT P10636 4/20 1.00
▸ KDM4E B2RXH2 2/20 1.00
▸ CACNA1B Q00975 1/20 1.00
▸ APBA1 Q02410 1/20 1.00
▸ MPL P40238 3/20 0.68
▸ NPC1 O15118 5/20 0.63
▸ RAB9A P51151 4/20 0.63
▸ CASP3 P42574 1/20 0.63
▸ SENP7 Q9BQF6 1/20 0.63
▸ SENP6 Q9GZR1 1/20 0.63
▸ ADORA3 P0DMS8 1/20 0.53
▸ POLB P06746 3/20 0.52
▸ GAA P10253 1/20 0.51
▸ PARP14 Q460N5 1/20 0.50
▸ PLA2G7 Q13093 1/20 0.48
▸ MAPK1 P28482 1/20 0.48
▸ APOBEC3A P31941 1/20 0.48
▸ APOBEC3G Q9HC16 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29405509 1.00 MEN1 (1.00) MEN1KMT2AMAPTKDM4ECACNA1B
SCHEMBL10719334 0.89 MEN1 (0.80) MEN1KMT2AMAPTKDM4ECACNA1B
SCHEMBL10987424 0.89 KMT2A (0.79) MEN1KMT2AMAPTKDM4ECACNA1B
SCHEMBL175806 0.88 KMT2A (0.78) MEN1KMT2AMAPTKDM4ECACNA1B
SCHEMBL5819536 0.86 KMT2A (0.76) MEN1KMT2AMAPTKDM4ECACNA1B
SCHEMBL31707424 0.86 KMT2A (0.76) MEN1KMT2AMAPTKDM4ECACNA1B
SCHEMBL10989850 0.86 KMT2A (0.75) MEN1KMT2AMAPTKDM4ECACNA1B
SCHEMBL9354492 0.82 KMT2A (0.70) MEN1KMT2AMAPTKDM4ECACNA1B
SCHEMBL22383840 0.82 MEN1 (0.70) MEN1KMT2AMAPTKDM4ECACNA1B
SCHEMBL20739018 0.82 MAPT (0.69) MEN1KMT2AMAPTKDM4ECACNA1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3702413-B1 PIGMENT DISPERSING AGENT, PIGMENT COMPOSITION, AND PIGMENT COLORING AGENT DAINICHISEIKA COLOR CHEM (JP) 2022-07-20 — — EP disclosed
US-10961227-B2 Pigment dispersing agent, pigment composition, and pigment coloring agent DAINICHISEIKA COLOR & CHEMICALS MFG. CO., LTD. (JP) 2021-03-30 — — US disclosed
EP-3447092-B1 BLACK AZO PIGMENT AND COLORANT DAINICHISEIKA COLOR CHEM (JP) 2021-03-24 — — EP disclosed
CN-111344358-B Pigment dispersant, pigment composition and pigment colorant 大日精化工业株式会社 2021-02-26 — — CN disclosed
US-20200377480-A1 PIGMENT DISPERSING AGENT, PIGMENT COMPOSITION, AND PIGMENT COLORING AGENT DAINICHISEIKA COLOR & CHEMICALS MFG. CO., LTD. (JP) 2020-12-03 — — US disclosed
EP-3702413-A1 PIGMENT DISPERSING AGENT, PIGMENT COMPOSITION, AND PIGMENT COLORING AGENT Dainichiseika Color & Chemicals Mfg. Co., Ltd. (JP) 2020-09-02 — — EP disclosed
CN-111344358-A Pigment dispersant, pigment composition and pigment colorant 大日精化工业株式会社 2020-06-26 — — CN disclosed
US-10344166-B2 Black azo pigment and colorant DAINICHISEIKA COLOR & CHEMICALS MFG. CO., LTD. (JP) 2019-07-09 — — US disclosed
US-20190048195-A1 BLACK AZO PIGMENT AND COLORANT DAINICHISEIKA COLOR & CHEMICALS MFG. CO., LTD. (JP) 2019-02-14 — — US disclosed
US-9822266-B2 Near infrared-reflecting/transmitting azo pigment, method for manufacturing near infrared-reflecting/transmitting azo pigment, colorant composition using said azo pigments, item-coloring method and colored item DAINICHISEIKA COLOR & CHEMICALS MFG. CO., LTD. (JP) 2017-11-21 — — US disclosed
US-6521038-B2 White pigment coated with near-infrared non-absorbing colorant DAINICHISEIKA COLOR & CHEMICALS MFG. CO., LTD. (JP) 2003-02-18 — — US disclosed
US-20020129739-A1 Near-infrared reflecting composite pigments DAINICHISEIKA COLOR & CHEMICALS MFG. CO., LTD. (JP) 2002-09-19 — — US disclosed
US-20020121228-A1 Near-infrared transmitting black azo pigments DAINICHISEIKA COLOR & CHEM. MFG. CO., LTD. (JP) 2002-09-05 — — US disclosed
EP-1219684-A1 Near-infrared transmitting black azo pigments DAINICHISEIKA COLOR & CHEMICALS MFG. CO. LTD. (JP) 2002-07-03 — — EP disclosed
EP-1217044-A2 Near-infrared reflecting composite pigments DAINICHISEIKA COLOR & CHEMICALS MFG. CO. LTD. (JP) 2002-06-26 — — EP disclosed
EP-0145348-B1 PHOTORECEPTOR KONICA CORPORATION (JP) 1988-08-10 — — EP disclosed
US-4647520-A Electrophotographic photoreceptor containing an azo compound KONOSHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1987-03-03 — — US disclosed
EP-0145348-A2 Photoreceptor KONICA CORPORATION (JP) 1985-06-19 — — EP disclosed
US-4224027-A Process for the production of water-insoluble azo dyestuffs on the fiber with polyphosphate HOECHST AKTIENGESELLSCHAFT (DE) 1980-09-23 — — US disclosed
US-4078887-A Concentrated stable solutions of coupling components for the ice color dyeing, their preparation and use HOECHST AKTIENGESELLSCHAFT (DT) 1978-03-14 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10961227-B2 Pigment dispersing agent, pigment composition, and pigment coloring agent RB1, TYR, IK MEN1 1929/4885KMT2A 131/4885MAPT 67/4885
US-20200377480-A1 PIGMENT DISPERSING AGENT, PIGMENT COMPOSITION, AND PIGMENT COLORING AGENT TYR, PIM1, RB1 MEN1 2671/4885KMT2A 302/4885MAPT 168/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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