SCHEMBL175806

SCHEMBL175806

O=C(Nc1ccccc1)c1cc2ccc3c4ccccc4[nH]c3c2cc1O

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 4/20 0.78
▸ MEN1 O00255 3/20 0.78
▸ KDM4E B2RXH2 2/20 0.78
▸ MAPT P10636 2/20 0.78
▸ CACNA1B Q00975 1/20 0.78
▸ APBA1 Q02410 1/20 0.78
▸ MPL P40238 4/20 0.73
▸ GAA P10253 1/20 0.55
▸ ADORA3 P0DMS8 1/20 0.46
▸ NPC1 O15118 3/20 0.45
▸ RAB9A P51151 3/20 0.45
▸ POLB P06746 1/20 0.45
▸ APP P05067 1/20 0.45
▸ KIF11 P52732 1/20 0.44
▸ CFTR P13569 1/20 0.44
▸ EGFR P00533 1/20 0.44
▸ SRC P12931 1/20 0.44
▸ TMPRSS4 Q9NRS4 1/20 0.44
▸ LMNA P02545 1/20 0.44
▸ SMN1; SMN2 Q16637 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10987424 0.91 KMT2A (0.79) KMT2AMEN1KDM4EMAPTCACNA1B
SCHEMBL14344726 0.89 MEN1 (0.64) KMT2AMEN1KDM4EMAPTCACNA1B
SCHEMBL9354492 0.89 KMT2A (0.70) KMT2AMEN1KDM4EMAPTCACNA1B
SCHEMBL10989850 0.88 KMT2A (0.75) KMT2AMEN1KDM4EMAPTCACNA1B
SCHEMBL5820002 0.88 MEN1 (1.00) KMT2AMEN1KDM4EMAPTCACNA1B
SCHEMBL29405509 0.88 MEN1 (1.00) KMT2AMEN1KDM4EMAPTCACNA1B
SCHEMBL9728924 0.88 KDM4E (0.63) KMT2AMEN1KDM4EMAPTCACNA1B
SCHEMBL14344704 0.86 MEN1 (0.61) KMT2AMEN1KDM4EMAPTCACNA1B
SCHEMBL20739018 0.86 MAPT (0.69) KMT2AMEN1KDM4EMAPTCACNA1B
SCHEMBL7618617 0.86 MEN1 (0.64) KMT2AMEN1KDM4EMAPTCACNA1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103597040-B High electrical insulating properties azo system black pigment, manufacture method, coloured composition, colorize method and dyed articles class DAINICHISEIKA COLOR & CHEMICALS MFG. CO.,LTD. (JP) 2016-01-27 — — CN claimed
CN-103282443-A Black azo pigment and process for production thereof, colored composition, coloring method, and colored articles DAINICHISEIKA COLOR CHEM 2013-09-04 — — CN claimed
US-5130443-A Process for the preparation of anilides XEROX CORPORATION (US) 1992-07-14 — — US claimed
JP-58122967-A — — None — — JP disclosed
JP-9048758-A — — None — — JP disclosed
JP-4236267-A — — None — — JP disclosed
JP-57203062-A — — None — — JP disclosed
EP-3702413-B1 PIGMENT DISPERSING AGENT, PIGMENT COMPOSITION, AND PIGMENT COLORING AGENT DAINICHISEIKA COLOR CHEM (JP) 2022-07-20 — — EP disclosed
US-10961227-B2 Pigment dispersing agent, pigment composition, and pigment coloring agent DAINICHISEIKA COLOR & CHEMICALS MFG. CO., LTD. (JP) 2021-03-30 — — US disclosed
CN-111344358-B Pigment dispersant, pigment composition and pigment colorant 大日精化工业株式会社 2021-02-26 — — CN disclosed
US-20200377480-A1 PIGMENT DISPERSING AGENT, PIGMENT COMPOSITION, AND PIGMENT COLORING AGENT DAINICHISEIKA COLOR & CHEMICALS MFG. CO., LTD. (JP) 2020-12-03 — — US disclosed
US-5130443-A Process for the preparation of anilides XEROX CORPORATION (US) 1992-07-14 — — US disclosed
US-4507471-A CHARGE TRANSFER COMPOUNDS FOR ELECTROPHOTOGRAPHIC ELECMENTS RICOH COMPANY, LTD. (JP) 1985-03-26 — — US disclosed
US-4507471-A CHARGE TRANSFER COMPOUNDS FOR ELECTROPHOTOGRAPHIC ELECMENTS RICOH COMPANY, LTD. (JP) 1985-03-26 — — US disclosed
US-4486519-A HIGH PHOTOSENSITYIVITY AND FLEXIBILITY RICOH COMPANY, LTD. (JP) 1984-12-04 — — US disclosed
US-4439506-A Multilayer electrophotographic element containing a trisazo charge carrier generating substance and an anthracene or divinyl benzene charge carrier transfer substance RICOH CO., LTD. (JP) 1984-03-27 — — US disclosed
US-4436800-A Multilayer electrophotographic element containing a trisazo charge carrier generating substance and a hydrazone charge carrier transfer substance RICOH CO., LTD. (JP) 1984-03-13 — — US disclosed
JP-S58122967-A NOVEL TRISAZO COMPOUND AND PRODUCTION THEREOF RICOH CO LTD 1983-07-21 — — JP disclosed
JP-S57203062-A NOVEL TRIAZO COMPOUND AND ITS PREPARATION RICOH CO LTD 1982-12-13 — — JP disclosed
US-4224027-A Process for the production of water-insoluble azo dyestuffs on the fiber with polyphosphate HOECHST AKTIENGESELLSCHAFT (DE) 1980-09-23 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10961227-B2 Pigment dispersing agent, pigment composition, and pigment coloring agent RB1, TYR, IK KMT2A 131/4885MEN1 1929/4885KDM4E 2825/4885
US-20200377480-A1 PIGMENT DISPERSING AGENT, PIGMENT COMPOSITION, AND PIGMENT COLORING AGENT TYR, PIM1, RB1 KMT2A 302/4885MEN1 2671/4885KDM4E 1608/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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