Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 8/20 | 0.62 |
| ▸ | HTR2A | P28223 | 2/20 | 0.62 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.62 |
| ▸ | DRD3 | P35462 | 6/20 | 0.57 |
| ▸ | HTR1A | P08908 | 4/20 | 0.57 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | HTR7 | P34969 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.54 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5822119 | 0.93 | DRD2 (0.54) | DRD2HTR2AMCHR1DRD3HTR1A | |
| SCHEMBL5805492 | 0.89 | DRD2 (0.72) | DRD2HTR2AMCHR1DRD3HTR1A | |
| Hydrochloric Acid SCHEMBL5821924 | 0.88 | DRD2 (0.49) | DRD2HTR2AMCHR1DRD3HTR1A | |
| Hydrochloric Acid SCHEMBL5808728 | 0.88 | DRD2 (0.71) | DRD2HTR2AMCHR1DRD3HTR1A | |
| Hydrochloric Acid SCHEMBL5815836 | 0.87 | DRD2 (0.52) | DRD2HTR2AMCHR1DRD3HTR1A | |
| SCHEMBL5816386 | 0.82 | DRD2 (0.56) | DRD2HTR2ADRD3HTR1AMEN1 | |
| SCHEMBL5807603 | 0.82 | DRD2 (0.63) | DRD2HTR2AMCHR1DRD3HTR1A | |
| SCHEMBL8251326 | 0.82 | DRD2 (0.53) | DRD2HTR2AMCHR1DRD3HTR1A | |
| Hydrochloric Acid SCHEMBL5805219 | 0.81 | DRD2 (0.62) | DRD2HTR2AMCHR1DRD3HTR1A | |
| SCHEMBL5820335 | 0.81 | DRD2 (0.59) | DRD2DRD3SLC6A4ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006117760-A1 | ADRENERGIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2006-11-09 | — | — | WO | claimed |