Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SHBG | P04278 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | NAAA | Q02083 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10680048 | 0.98 | TSHR (0.40) | TSHRSHBGEPHX1NAAAKDM4E | |
| SCHEMBL10684687 | 0.90 | TSHR (0.46) | TSHRSHBG | |
| SCHEMBL10683117 | 0.80 | NAAA (0.37) | SHBGEPHX1NAAAKDM4E | |
| SCHEMBL12711502 | 0.80 | TSHR (0.33) | TSHR | |
| SCHEMBL5859489 | 0.78 | PDE4D (0.34) | TSHR | |
| SCHEMBL9185507 | 0.77 | NAAA (0.42) | EPHX1NAAAALDH1A1 | |
| SCHEMBL529784 | 0.76 | KDM4E (0.37) | EPHX1KDM4E | |
| SCHEMBL21250764 | 0.76 | NAAA (0.45) | NAAAALDH1A1 | |
| SCHEMBL21586586 | 0.74 | TP53 (0.46) | EPHX1KDM4EALDH1A1 | |
| SCHEMBL19366102 | 0.74 | TP53 (0.46) | EPHX1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230174496-A1 | Synthesis of Vinylic Protected Alcohol Intermediates | AMGEN INC. (US) | 2023-06-08 | — | — | US | disclosed |
| WO-2006084208-A2 | USE OF WATER STRUCTURANTS TO PROVIDE FABRIC CARE BENEFITS IN A NON-AQUEOUS FABRIC TREATMENT SYSTEM | THE PROCTER & GAMBLE COMPANY (US) | 2006-08-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230174496-A1 | Synthesis of Vinylic Protected Alcohol Intermediates | MCL1, BCL2A1, BAK1 | TSHR 2499/4885SHBG 3772/4885EPHX1 3053/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.