Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.48 |
| ▸ | BACE1 | P56817 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | MIF | P14174 | 1/20 | 0.37 |
| ▸ | TYR | P14679 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ATP2A2 | P16615 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30443573 | 0.88 | ESR1 (0.56) | ESR1ESR2BACE1ALDH1A1HSD17B10 | |
| SCHEMBL29802337 | 0.88 | ESR1 (0.56) | ESR1ESR2BACE1ALDH1A1HSD17B10 | |
| SCHEMBL9816996 | 0.88 | ESR1 (0.56) | ESR1ESR2BACE1ALDH1A1HSD17B10 | |
| SCHEMBL29459479 | 0.88 | ESR1 (0.56) | ESR1ESR2BACE1ALDH1A1HSD17B10 | |
| SCHEMBL9816983 | 0.88 | ESR1 (0.56) | ESR1ESR2BACE1ALDH1A1HSD17B10 | |
| SCHEMBL9817038 | 0.88 | ESR1 (0.56) | ESR1ESR2BACE1ALDH1A1HSD17B10 | |
| SCHEMBL9817137 | 0.88 | ESR1 (0.56) | ESR1ESR2BACE1ALDH1A1HSD17B10 | |
| SCHEMBL3303467 | 0.88 | ESR1 (0.56) | ESR1ESR2BACE1ALDH1A1HSD17B10 | |
| SCHEMBL297971 | 0.88 | ESR1 (0.56) | ESR1ESR2BACE1ALDH1A1HSD17B10 | |
| SCHEMBL9817120 | 0.88 | ESR1 (0.56) | ESR1ESR2BACE1ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020111456-A1 | Method of polycarbonate preparation | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2002-08-15 | — | — | US | claimed |
| EP-1307499-B2 | CONTINUOUS PREPARATION OF POLYCARBONATE | GEN ELECTRIC (US) | 2012-02-15 | — | — | EP | disclosed |
| EP-1307499-B1 | CONTINUOUS PREPARATION OF POLYCARBONATE | GEN ELECTRIC (US) | 2006-10-25 | — | — | EP | disclosed |
| US-6562937-B2 | Endcapping with phenol | GENERAL ELECTRIC COMPANY | 2003-05-13 | — | — | US | disclosed |