Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | HTR2B | P41595 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24328520 | 0.96 | ALDH1A1 (0.39) | MAPTMEN1GFERKMT2ASMN1; SMN2 | |
| SCHEMBL30773544 | 0.96 | ALDH1A1 (0.39) | MAPTMEN1GFERKMT2ASMN1; SMN2 | |
| SCHEMBL30503607 | 0.88 | MAPT (0.47) | MAPTMEN1GFERKMT2ASMN1; SMN2 | |
| SCHEMBL9452622 | 0.88 | MAPT (0.47) | MAPTMEN1GFERKMT2ASMN1; SMN2 | |
| SCHEMBL29375067 | 0.78 | KDM4E (0.41) | MAPTKMT2ASMN1; SMN2ALDH1A1CYP3A4 | |
| SCHEMBL4846663 | 0.78 | KDM4E (0.41) | MAPTKMT2ASMN1; SMN2ALDH1A1CYP3A4 | |
| SCHEMBL6610894 | 0.78 | HTR2C (0.48) | MAPTALDH1A1CYP3A4BCHEACHE | |
| SCHEMBL7117117 | 0.77 | TDP1 (0.50) | MAPTMEN1GFERKMT2ASMN1; SMN2 | |
| SCHEMBL31731530 | 0.76 | MAPT (0.44) | MAPTMEN1GFERKMT2ASMN1; SMN2 | |
| SCHEMBL10463782 | 0.76 | HTR2C (0.40) | HTR2AHTR2CHTR2BKDM4ECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006023158-A2 | MINERALOCORTICOID RECEPTOR MODULATOR COMPOUNDS AND METHODS, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS | LIGAND PHARMACEUTICALS, INC. (US) | 2006-03-02 | — | — | WO | disclosed |