Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXTR | P30559 | 2/20 | 0.66 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.66 |
| ▸ | CPT1A | P50416 | 6/20 | 0.46 |
| ▸ | CPT1B | Q92523 | 6/20 | 0.46 |
| ▸ | CPT2 | P23786 | 4/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 7/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5820190 | 1.00 | OXTR (0.66) | OXTRAVPR1ACPT1ACPT1BCPT2 | |
| SCHEMBL3876738 | 1.00 | OXTR (0.66) | OXTRAVPR1ACPT1ACPT1BCPT2 | |
| SCHEMBL5435083 | 0.95 | OXTR (0.59) | OXTRAVPR1ACPT1ACPT1BCPT2 | |
| SCHEMBL5434126 | 0.92 | OXTR (0.65) | OXTRAVPR1ACPT1ACPT1BCPT2 | |
| SCHEMBL5819517 | 0.92 | OXTR (0.65) | OXTRAVPR1ACPT1ACPT1BCPT2 | |
| SCHEMBL5424527 | 0.91 | OXTR (0.57) | OXTRAVPR1ACPT1ACPT1BCPT2 | |
| SCHEMBL5440497 | 0.91 | OXTR (0.70) | OXTRAVPR1ACPT1ACPT1BCPT2 | |
| SCHEMBL5433052 | 0.90 | OXTR (0.57) | OXTRAVPR1ACPT1ACPT1BCPT2 | |
| SCHEMBL5436199 | 0.90 | OXTR (0.55) | OXTRAVPR1ACPT1ACPT1BCPT2 | |
| SCHEMBL5427651 | 0.89 | OXTR (0.79) | OXTRAVPR1ACPT1ACPT1BCPT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006082454-A1 | PROCESS FOR THE PREPARATION OF RACEMIC AND OPTICALLY ACTIVE 4-CHLORO-3-[5-CHLORO-1-(2,4-DIMETHOXYBENZYL)-3-ALKYL-2-OXO-2,3-DIHYDRO-1H-INDOL-3-YL]BENZOIC ACID DERIVATIVES USING A PHASE TRANSFER CATALYST | SANOFI-AVENTIS (FR) | 2006-08-10 | — | — | WO | disclosed |