Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.67 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | DHODH | Q02127 | 11/20 | 0.61 |
| ▸ | CDC7 | O00311 | 3/20 | 0.61 |
| ▸ | DBF4 | Q9UBU7 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.57 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.53 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 1/20 | 0.53 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.53 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5813230 | 0.90 | CDC7 (0.59) | ALDH1A1HSD17B10HPGDDHODHCDC7 | |
| SCHEMBL11286051 | 0.87 | ALDH1A1 (0.70) | ALDH1A1HSD17B10HPGDDHODHCDC7 | |
| SCHEMBL2885006 | 0.85 | NPC1 (0.59) | ALDH1A1HSD17B10HPGDDHODHCDC7 | |
| SCHEMBL1919885 | 0.82 | ALDH1A1 (0.61) | ALDH1A1HSD17B10HPGDDHODHCDC7 | |
| SCHEMBL8823153 | 0.82 | ALDH1A1 (0.75) | ALDH1A1HSD17B10HPGDDHODHCDC7 | |
| SCHEMBL5820225 | 0.82 | CDC7 (0.52) | ALDH1A1HSD17B10HPGDDHODHCDC7 | |
| SCHEMBL16075306 | 0.81 | ALDH1A1 (0.81) | ALDH1A1HSD17B10HPGDDHODHCDC7 | |
| SCHEMBL4503056 | 0.81 | CDC7 (0.88) | ALDH1A1HSD17B10HPGDDHODHCDC7 | |
| SCHEMBL1919084 | 0.81 | ALDH1A1 (0.74) | ALDH1A1HSD17B10HPGDDHODHCDC7 | |
| SCHEMBL6502690 | 0.81 | ALDH1A1 (0.73) | ALDH1A1HSD17B10HPGDDHODHCDC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006085815-A1 | THIAZOLE DERIVATIVES, THEIR PROCESS FOR THEIR PREPARATION AND THEIR USE IN THERAPY | ASTRAZENECA AB (SE) | 2006-08-17 | — | — | WO | disclosed |
| WO-2006085815-A1 | THIAZOLE DERIVATIVES, THEIR PROCESS FOR THEIR PREPARATION AND THEIR USE IN THERAPY | ASTRAZENECA AB (SE) | 2006-08-17 | — | — | WO | disclosed |