Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 6/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 7/20 | 0.43 |
| ▸ | THRA | P10827 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | PPARA | Q07869 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MPC2 | O95563 | 2/20 | 0.41 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5533136 | 0.89 | PTPN1 (0.46) | PPARGPTPN1FFAR1THRATHRB | |
| SCHEMBL1385478 | 0.88 | PPARG (0.44) | PPARGPTPN1FFAR1THRATHRB | |
| Hydrochloric Acid SCHEMBL4173102 | 0.87 | PPARG (0.44) | PPARGPTPN1FFAR1THRATHRB | |
| SCHEMBL3594379 | 0.84 | PPARG (0.48) | PPARGPTPN1FFAR1THRATHRB | |
| SCHEMBL1387071 | 0.84 | PPARG (0.47) | PPARGPTPN1FFAR1THRATHRB | |
| SCHEMBL13866919 | 0.82 | PTPN1 (0.46) | PPARGPTPN1FFAR1THRATHRB | |
| SCHEMBL1386854 | 0.82 | PTPN1 (0.46) | PPARGPTPN1FFAR1THRATHRB | |
| SCHEMBL13875580 | 0.81 | PTPN1 (0.46) | PPARGPTPN1FFAR1THRATHRB | |
| Hydrochloric Acid SCHEMBL3870101 | 0.81 | PTPN1 (0.46) | PPARGPTPN1FFAR1THRATHRB | |
| SCHEMBL13911989 | 0.80 | ALDH1A1 (0.43) | PPARGPTPN1FFAR1THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006125285-A1 | INSULIN SENSITIZATION TO SLOW DOWN PUBERTAL TEMPO AND TO AUGMENT PUBERTAL GROWTH | K.U. LEUVEN RESEARCH AND DEVELOPMENT (BE) | 2006-11-30 | — | — | WO | disclosed |