Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5491743 | 0.83 | LMNA (0.49) | MCHR1LMNAHPGDALDH1A1MAPT | |
| SCHEMBL5491746 | 0.83 | LMNA (0.49) | MCHR1LMNAHPGDALDH1A1MAPT | |
| SCHEMBL5494050 | 0.80 | CYP1A2 (0.49) | LMNAHPGDALDH1A1MAPTCYP1A2 | |
| Methylpiperazine SCHEMBL5498097 | 0.80 | HPGD (0.56) | HPGDALDH1A1MAPTCYP1A2CYP3A4 | |
| SCHEMBL15513480 | 0.74 | CYP1A2 (0.48) | LMNAHPGDALDH1A1MAPTCYP1A2 | |
| SCHEMBL5497389 | 0.70 | CYP1A2 (0.46) | HPGDALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL5487654 | 0.70 | CYP1A2 (0.62) | ALDH1A1MAPTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL5487655 | 0.70 | CYP1A2 (0.62) | ALDH1A1MAPTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL5808562 | 0.70 | CYP1A2 (0.62) | ALDH1A1MAPTCYP1A2CYP3A4CYP2C9 | |
| Methylpiperazine SCHEMBL5496267 | 0.69 | HPGD (0.52) | HPGDALDH1A1CYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006103527-A1 | AROMATIC SUBSTITUTED PENTADIENOIC ACID AMIDE FOR COMBINATION WITH ANTI-INFECTIVE DRUGS | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2006-10-05 | — | — | WO | disclosed |