Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.65 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.65 |
| ▸ | TSHR | P16473 | 5/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | BLM | P54132 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | GMNN | O75496 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29440398 | 0.79 | GABRA1 (0.71) | GABRA1GABRB2TSHRPOLBCA2 | |
| SCHEMBL51565 | 0.79 | GABRA1 (0.71) | GABRA1GABRB2TSHRPOLBCA2 | |
| SCHEMBL29531559 | 0.79 | GABRA1 (1.00) | GABRA1GABRB2TSHRPOLBCA2 | |
| SCHEMBL11597764 | 0.79 | GABRA1 (0.71) | GABRA1GABRB2TSHRPOLBCA2 | |
| SCHEMBL43297 | 0.79 | GABRA1 (1.00) | GABRA1GABRB2TSHRPOLBCA2 | |
| SCHEMBL15485453 | 0.79 | GABRA1 (1.00) | GABRA1GABRB2TSHRPOLBCA2 | |
| SCHEMBL31340010 | 0.77 | GABRA1 (0.68) | GABRA1GABRB2TSHRPOLBCA2 | |
| Benzene SCHEMBL1841233 | 0.77 | GABRA1 (0.95) | GABRA1GABRB2TSHRPOLBCA2 | |
| Ethane SCHEMBL5264203 | 0.77 | GABRA1 (0.95) | GABRA1GABRB2TSHRPOLBCA2 | |
| SCHEMBL570520 | 0.77 | GABRA1 (0.68) | GABRA1GABRB2TSHRPOLBCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006086731-A2 | METHOD FOR IDENTIFYING THE RISK OF PRETERM DELIVERY | THE GOV'T.T OF THE USA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH & HUMAN SERVICES (US) | 2006-08-17 | — | — | WO | disclosed |