Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 1/20 | 0.52 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.52 |
| ▸ | ESR1 | P03372 | 5/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | APEX1 | P27695 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | ELANE | P08246 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | PTP4A3 | O75365 | 1/20 | 0.50 |
| ▸ | GMNN | O75496 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Flaviolin SCHEMBL703160 | 0.84 | BCL2 (0.52) | BCL2MCL1ESR1ESR2POLB | |
| SCHEMBL22785964 | 0.81 | MAPT (0.41) | BCL2MCL1ESR1ESR2POLB | |
| SCHEMBL20364866 | 0.81 | PIM1 (0.59) | ESR1ESR2POLBMAPTKMT2A | |
| SCHEMBL5821956 | 0.80 | KDM4E (0.58) | MCL1POLBMAPTKMT2AALDH1A1 | |
| SCHEMBL30669738 | 0.80 | MAPT (0.56) | BCL2MCL1ESR1ESR2POLB | |
| SCHEMBL2315695 | 0.80 | MAPT (0.56) | BCL2MCL1ESR1ESR2POLB | |
| SCHEMBL2771631 | 0.78 | BCL2 (0.76) | BCL2MCL1ESR1ESR2POLB | |
| SCHEMBL29390162 | 0.76 | ESR1 (0.77) | BCL2MCL1ESR1ESR2POLB | |
| SCHEMBL5968219 | 0.76 | ESR1 (0.77) | BCL2MCL1ESR1ESR2POLB | |
| SCHEMBL9178309 | 0.74 | BCL2 (0.48) | BCL2MCL1ESR1ESR2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006107827-A1 | SKIN BONDING PROCESS | CREIGHTON UNIVERSITY (US) | 2006-10-12 | — | — | WO | disclosed |