Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 6/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 6/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.39 |
| ▸ | XIAP | P98170 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18992102 | 0.82 | KDM4E (0.38) | BCL2MCL1KDM4EMAPTALDH1A1 | |
| SCHEMBL30002673 | 0.82 | XIAP (0.39) | KDM4EMAPTALDH1A1CYP3A4HPGD | |
| SCHEMBL30003252 | 0.82 | KDM4E (0.38) | BCL2MCL1KDM4EMAPTALDH1A1 | |
| SCHEMBL8993580 | 0.82 | XIAP (0.39) | KDM4EMAPTALDH1A1CYP3A4HPGD | |
| SCHEMBL6683984 | 0.79 | GAPDH (0.49) | BCL2MCL1KDM4EMAPTALDH1A1 | |
| SCHEMBL973797 | 0.77 | CA1 (0.46) | CYP3A4XIAPP4HB | |
| SCHEMBL8821657 | 0.76 | BCL2 (0.74) | BCL2MCL1MAPTALDH1A1CYP3A4 | |
| SCHEMBL5817037 | 0.76 | ESR2 (0.61) | KDM4EMAPTALDH1A1CYP3A4HPGD | |
| SCHEMBL5811756 | 0.76 | ESR2 (0.61) | BCL2MCL1KDM4EMAPTALDH1A1 | |
| SCHEMBL30004162 | 0.76 | ESR2 (0.61) | BCL2MCL1KDM4EMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0498707-B1 | Process of dyeing keratinous fibers with a mono- or di-hydroxyindole and a non-oxidative aromatic carbonyl derivative and dyeing agent | OREAL (FR) | 1995-08-02 | — | — | EP | claimed |
| EP-0498707-A1 | Process of dyeing keratinous fibers with a mono- or di-hydroxyindole and a non-oxidative aromatic carbonyl derivative and dyeing agent | L'OREAL (FR) | 1992-08-12 | — | — | EP | claimed |
| US-4888026-A | HAIR DYES; OXIDATION RESISTANCE | L'OREAL (FR) | 1989-12-19 | — | — | US | claimed |
| EP-0498707-B1 | Process of dyeing keratinous fibers with a mono- or di-hydroxyindole and a non-oxidative aromatic carbonyl derivative and dyeing agent | OREAL (FR) | 1995-08-02 | — | — | EP | disclosed |
| US-5275626-A | Hair dyes | L'OREAL (FR) | 1994-01-04 | — | — | US | disclosed |
| EP-0498707-A1 | Process of dyeing keratinous fibers with a mono- or di-hydroxyindole and a non-oxidative aromatic carbonyl derivative and dyeing agent | L'OREAL (FR) | 1992-08-12 | — | — | EP | disclosed |
| US-4888026-A | HAIR DYES; OXIDATION RESISTANCE | L'OREAL (FR) | 1989-12-19 | — | — | US | disclosed |