Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28966851 | 0.80 | TSHR (0.43) | TSHROPRM1OPRD1OPRK1CYP1A2 | |
| SCHEMBL7886211 | 0.73 | NPSR1 (0.52) | TSHRKDM4EHPGDRAB9ASMN1; SMN2 | |
| SCHEMBL827023 | 0.72 | CYP1A2 (0.46) | TSHRKDM4ECYP1A2CYP2D6 | |
| SCHEMBL24234047 | 0.71 | KMT2A (0.46) | TSHRKDM4ERAB9A | |
| SCHEMBL873994 | 0.71 | HPGD (0.72) | KDM4EHPGDRAB9ASMN1; SMN2 | |
| SCHEMBL133668 | 0.71 | KDM4E (0.67) | TSHRKDM4EHPGDRAB9ASMN1; SMN2 | |
| SCHEMBL10141202 | 0.71 | — | — | |
| SCHEMBL21114388 | 0.71 | TSHR (0.57) | TSHRKDM4ECYP1A2CYP2D6GAA | |
| SCHEMBL28298 | 0.71 | — | — | |
| SCHEMBL10141203 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006110918-A1 | PYRROLE COMPOUNDS AND USES THEREOF | AMBIT BIOSCIENCES CORPORATION (US) | 2006-10-19 | — | — | WO | disclosed |
| EP-0680963-B1 | (Hydroxyphenylamino)carbonyl pyrroles | WARNER LAMBERT CO (US) | 2001-11-21 | — | — | EP | disclosed |
| EP-0680963-B1 | (Hydroxyphenylamino)carbonyl pyrroles | WARNER LAMBERT CO (US) | 2001-11-21 | — | — | EP | disclosed |
| EP-0680963-A1 | (Hydroxyphenylamino)carbonyl pyrroles | WARNER-LAMBERT COMPANY (US) | 1995-11-08 | — | — | EP | disclosed |
| EP-0680963-A1 | (Hydroxyphenylamino)carbonyl pyrroles | WARNER-LAMBERT COMPANY (US) | 1995-11-08 | — | — | EP | disclosed |
| US-5385929-A | Anticholesterol agents | WARNER-LAMBERT COMPANY (US) | 1995-01-31 | — | — | US | disclosed |
| US-5385929-A | Anticholesterol agents | WARNER-LAMBERT COMPANY (US) | 1995-01-31 | — | — | US | disclosed |