Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.48 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.43 |
| ▸ | HTR2A | P28223 | 4/20 | 0.41 |
| ▸ | HTR2C | P28335 | 4/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | AQP1 | P29972 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HTR3A | P46098 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5792689 | 0.92 | HRH3 (0.52) | HRH3HTR2AHTR2CADRB1DRD2 | |
| SCHEMBL5792693 | 0.92 | HRH3 (0.52) | HRH3HTR2AHTR2CADRB1DRD2 | |
| SCHEMBL5792518 | 0.85 | HRH3 (0.48) | HRH3HTR2AHTR2CHRH4HTR2B | |
| SCHEMBL5792463 | 0.83 | HRH3 (0.53) | HRH3HTR2AHTR2CADRB1HTR2B | |
| SCHEMBL5795029 | 0.82 | HRH3 (0.52) | HRH3HTR2AHTR2CHTR2BHTR1A | |
| SCHEMBL5795007 | 0.82 | HRH3 (0.55) | HRH3HTR2AHTR2CADRB1HRH4 | |
| SCHEMBL4607050 | 0.77 | PRKAB2 (0.53) | PTPN11HTR2AHTR2CHTR2BAQP1 | |
| SCHEMBL5791140 | 0.77 | HRH3 (0.55) | HRH3HTR2AHTR2CHTR2BHTR1A | |
| SCHEMBL5807660 | 0.77 | HRH3 (0.55) | HRH3HTR2AHTR2CADRB1HRH4 | |
| SCHEMBL5791988 | 0.76 | HRH3 (0.53) | HRH3DRD2DRD3CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006000902-A1 | DIHYDROBENZOFURAN COMPOUNDS AND USES THEREOF | PFIZER PRODUCTS INC. (US) | 2006-01-05 | — | — | WO | disclosed |