Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 3/20 | 0.60 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.60 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.60 |
| ▸ | MCHR1 | Q99705 | 11/20 | 0.40 |
| ▸ | KCNK3 | O14649 | 4/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2389383 | 0.90 | RXRA (0.61) | RXRANR1H2NR1H3MCHR1KCNK3 | |
| SCHEMBL2392062 | 0.89 | RXRA (0.63) | RXRANR1H2NR1H3MCHR1KCNK3 | |
| SCHEMBL2389509 | 0.87 | RXRA (0.63) | RXRANR1H2NR1H3MCHR1KCNK3 | |
| Dimethylamine SCHEMBL5821096 | 0.86 | RXRA (0.63) | RXRANR1H2NR1H3MCHR1KCNK3 | |
| SCHEMBL2391037 | 0.86 | RXRA (0.61) | RXRANR1H2NR1H3MCHR1KCNK3 | |
| SCHEMBL2391077 | 0.85 | RXRA (0.59) | RXRANR1H2NR1H3MCHR1KCNK3 | |
| SCHEMBL14214340 | 0.85 | RXRA (0.75) | RXRANR1H2NR1H3KCNK3MAPT | |
| SCHEMBL2387401 | 0.84 | RXRA (0.62) | RXRANR1H2NR1H3KCNK3MAPK14 | |
| SCHEMBL2389385 | 0.83 | RXRA (0.65) | RXRANR1H2NR1H3MCHR1KCNK3 | |
| SCHEMBL5793484 | 0.83 | RXRA (0.70) | RXRANR1H2NR1H3KCNK3TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006025979-A9 | MODULATORS OF NUCLEAR RECEPTORS | EXELIXIS INC (US) | 2006-04-20 | — | — | WO | claimed |