Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | RET | P07949 | 5/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3833011 | 0.92 | MAPT (0.37) | MAPK1PIK3CAMAPK14RETSYK | |
| SCHEMBL5822946 | 0.89 | SMN1; SMN2 (0.38) | MAPK1PIK3CAMAPK14RETSYK | |
| SCHEMBL5822970 | 0.87 | MAPT (0.48) | BRD4ALDH1A1HPGDSMN1; SMN2MAPT | |
| SCHEMBL3826198 | 0.87 | CNR1 (0.39) | MAPK14RETALDH1A1CNR1KDM4E | |
| SCHEMBL5822553 | 0.87 | PTK2 (0.38) | MAPK1PIK3CAMAPK14RETSYK | |
| SCHEMBL4391744 | 0.86 | RAB9A (0.42) | BRD4SMN1; SMN2MAPTKDM4ETSHR | |
| SCHEMBL4793494 | 0.86 | RET (0.36) | MAPK1RETSYKALDH1A1HPGD | |
| SCHEMBL3830189 | 0.86 | MAPT (0.37) | MAPK14RETSYKALDH1A1HPGD | |
| SCHEMBL3833160 | 0.85 | RET (0.38) | RETSYKPTK2CNR1KDM4E | |
| SCHEMBL3828088 | 0.84 | MAPT (0.44) | MAPK1PIK3CAMAPK14RETSYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006124897-A2 | METHODS AND COMPOSITIONS FOR IMPROVING COGNITION | LEXICON GENETICS INCORPORATED (US) | 2006-11-23 | — | — | WO | disclosed |