Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 8/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 4/20 | 0.41 |
| ▸ | MAOB | P27338 | 4/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.40 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.40 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4419049 | 0.88 | ITGB3 (0.47) | ITGB3ITGA2BAOC3SCN3A | |
| SCHEMBL4419052 | 0.88 | ITGB3 (0.47) | ITGB3ITGA2BAOC3SCN3A | |
| SCHEMBL4563539 | 0.80 | SCN3A (0.52) | GPR84ITGB3ITGA2BAOC3MAOB | |
| SCHEMBL4427021 | 0.80 | SCN3A (0.52) | GPR84ITGB3ITGA2BAOC3MAOB | |
| SCHEMBL3507011 | 0.77 | ITGB3 (0.49) | ITGB3ITGA2BAOC3 | |
| SCHEMBL3507015 | 0.77 | ITGB3 (0.49) | ITGB3ITGA2BAOC3 | |
| SCHEMBL13322633 | 0.74 | GRM5 (0.51) | ITGB3ITGA2B | |
| SCHEMBL4427015 | 0.73 | ITGB3 (0.47) | ITGB3ITGA2BMAOBSCN3A | |
| SCHEMBL4427018 | 0.73 | ITGB3 (0.47) | ITGB3ITGA2BMAOBSCN3A | |
| SCHEMBL4424255 | 0.73 | MAOB (0.60) | ITGB3ITGA2BMAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006138475-A2 | MAO-B INHIBITORS USEFUL FOR TREATING OBESITY | JENRIN DISCOVERY (US) | 2006-12-28 | — | — | WO | claimed |
| WO-2006138475-A2 | MAO-B INHIBITORS USEFUL FOR TREATING OBESITY | JENRIN DISCOVERY (US) | 2006-12-28 | — | — | WO | disclosed |