Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 8/20 | 0.42 |
| ▸ | PPARA | Q07869 | 8/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5822905 | 0.83 | PPARA (0.44) | CYP1A2CYP2D6ATML3MBTL1PPARG | |
| SCHEMBL3248391 | 0.83 | PPARG (0.59) | CYP1A2L3MBTL1PPARGPPARACYP2C19 | |
| SCHEMBL27589060 | 0.81 | KMT2A (0.43) | CYP1A2CYP2D6ATML3MBTL1PPARG | |
| Acetic Acid SCHEMBL10738328 | 0.80 | PPARA (0.42) | CYP1A2CYP2D6ATML3MBTL1PPARG | |
| SCHEMBL10756296 | 0.80 | POLB (0.41) | L3MBTL1PPARGPPARAALDH1A1 | |
| SCHEMBL10907465 | 0.78 | PPARG (0.42) | CYP1A2CYP2D6ATML3MBTL1PPARG | |
| SCHEMBL28490551 | 0.77 | CTSK (0.44) | PPARGPPARA | |
| SCHEMBL4790308 | 0.76 | PPARA (0.39) | CYP1A2CYP2D6ATML3MBTL1PPARG | |
| SCHEMBL25442179 | 0.76 | KMT2A (0.45) | MEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL29114571 | 0.76 | CYP1A2 (0.50) | CYP1A2CYP2D6ATML3MBTL1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006058199-A1 | METHODS OF MODULATING HIGH-DENSITY LIPOPROTEIN CHOLESTEROL LEVELS AND PHARMACEUTICAL FORMULATIONS FOR THE SAME | FAZIX CORPORATION (US) | 2006-06-01 | — | — | WO | disclosed |
| US-20060111346-A1 | Methods of modulating high-density lipoprotein cholesterol levels and pharmaceutical formulations for the same | FAZIX CORPORATION. | 2006-05-25 | — | — | US | disclosed |
| US-H349-H | Inert solid compositions which become chemically reactive when molten | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 1987-10-06 | — | — | US | disclosed |
| EP-0001721-B1 | N-CYANO- AND N-ALKYNYL-2-(SUBSTITUTED PHENOXY)BUTYRAMIDES AND THE USE THEREOF AS MILDEWICIDES | STAUFFER CHEMICAL COMPANY (US) | 1981-09-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060111346-A1 | Methods of modulating high-density lipoprotein cholesterol levels and pharmaceutical formulations for the same | HDLBP, LDLR, CETP | CYP1A2 252/4885CYP2D6 398/4885ATM 3318/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.