Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 17/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.44 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4897276 | 0.88 | HDAC1 (0.68) | HDAC1KCNH2 | |
| SCHEMBL4890641 | 0.78 | HDAC1 (0.67) | HDAC1KCNH2HDAC3HDAC2HDAC4 | |
| SCHEMBL4887589 | 0.78 | HDAC1 (0.47) | HDAC1HDAC3HDAC2NCOR2 | |
| SCHEMBL4897235 | 0.75 | HDAC1 (0.71) | HDAC1KCNH2HDAC3HDAC2HDAC4 | |
| SCHEMBL4898587 | 0.74 | HDAC1 (0.86) | HDAC1KCNH2HDAC3HDAC2ABL1 | |
| SCHEMBL4897259 | 0.74 | HDAC1 (0.69) | HDAC1KCNH2HDAC2 | |
| SCHEMBL4891759 | 0.73 | HDAC1 (0.96) | HDAC1KCNH2 | |
| SCHEMBL4898273 | 0.73 | HDAC1 (1.00) | HDAC1KCNH2HDAC3HDAC2HDAC4 | |
| SCHEMBL8265319 | 0.73 | HDAC1 (0.59) | HDAC1KCNH2HDAC3HDAC2HDAC4 | |
| SCHEMBL4899357 | 0.73 | HDAC1 (0.70) | HDAC1KCNH2HDAC3HDAC2HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006077387-A2 | NOVEL BENZAMIDE DERIVATIVES | ASTRAZENECA AB (SE) | 2006-07-27 | — | — | WO | disclosed |