SCHEMBL5821828

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL30416459	0.90	BTK (0.61)	BTKLCKLYNNUDT14NUDT5
	SCHEMBL6430366	0.89	BTK (0.69)	BTKLCKLYNNUDT14NUDT5
	SCHEMBL7140005	0.88	BTK (0.66)	BTKLCKLYNNUDT14NUDT5
	SCHEMBL5821832	0.87	BTK (0.46)	BTKLCKLYNNUDT14NUDT5
	SCHEMBL24196933	0.84	BTK (0.61)	BTKLCKLYNNUDT14NUDT5
	SCHEMBL15160873	0.83	BTK (0.69)	BTKLCKLYNNUDT14NUDT5
	SCHEMBL5800914	0.83	BTK (0.60)	BTKLCKLYNNUDT14NUDT5
	SCHEMBL6431386	0.83	BTK (0.74)	BTKLCKLYNNUDT14NUDT5
	SCHEMBL6431394	0.83	BTK (0.74)	BTKLCKLYNNUDT14NUDT5
	SCHEMBL6431380	0.83	BTK (0.74)	BTKLCKLYNNUDT14NUDT5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.