Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 20/20 | 0.66 |
| ▸ | EGFR | P00533 | 4/20 | 0.60 |
| ▸ | TEC | P42680 | 3/20 | 0.59 |
| ▸ | BMX | P51813 | 3/20 | 0.59 |
| ▸ | LYN | P07948 | 3/20 | 0.59 |
| ▸ | TXK | P42681 | 2/20 | 0.59 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.59 |
| ▸ | ITK | Q08881 | 2/20 | 0.59 |
| ▸ | LCK | P06239 | 2/20 | 0.59 |
| ▸ | FLT3 | P36888 | 2/20 | 0.59 |
| ▸ | BLK | P51451 | 2/20 | 0.59 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.59 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.59 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.59 |
| ▸ | LATS1 | O95835 | 1/20 | 0.59 |
| ▸ | NUDT14 | O95848 | 1/20 | 0.59 |
| ▸ | ABL1 | P00519 | 1/20 | 0.59 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.59 |
| ▸ | FYN | P06241 | 1/20 | 0.59 |
| ▸ | PGR | P06401 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5800914 | 0.90 | BTK (0.60) | BTKEGFRTECBMXLYN | |
| SCHEMBL6430366 | 0.90 | BTK (0.69) | BTKEGFRLYNITKLCK | |
| SCHEMBL5821828 | 0.88 | BTK (0.61) | BTKEGFRTECBMXLYN | |
| SCHEMBL7144296 | 0.85 | BTK (0.73) | BTKEGFRTECBMXLYN | |
| SCHEMBL15155291 | 0.85 | BTK (0.79) | BTKEGFRTECBMXLYN | |
| SCHEMBL22777861 | 0.84 | BTK (0.82) | BTKEGFRTECBMXLYN | |
| SCHEMBL6430741 | 0.82 | BTK (0.82) | BTKEGFRTECBMXLYN | |
| SCHEMBL25178130 | 0.82 | BTK (0.75) | BTKEGFRTECBMXLYN | |
| SCHEMBL26095884 | 0.81 | BTK (0.74) | BTKEGFRTECBMXLYN | |
| SCHEMBL26095873 | 0.81 | BTK (0.74) | BTKEGFRTECBMXLYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1520298-A | Pyrazolopyrimidines as therapeutic agents | �����ʩ���عɷݹ�˾ | 2004-08-11 | — | — | CN | disclosed |
| US-6660744-B1 | Kinase inhibitors | ABBOTT GMBH & CO. KG (DE) | 2003-12-09 | — | — | US | disclosed |
| CN-1390219-A | Pyrazolopyrimidines as therapeutic agents | ABBOTT AG (DE) | 2003-01-08 | — | — | CN | disclosed |