Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.54 |
| ▸ | RXRA | P19793 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | PLA2G4B | P0C869 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | RXRB | P28702 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1162595 | 0.84 | LMNA (0.63) | PPARGRXRACYP3A4L3MBTL1LMNA | |
| SCHEMBL943063 | 0.82 | PPARG (0.58) | PPARGRXRACYP3A4PLA2G4BRXRB | |
| SCHEMBL14855164 | 0.79 | LMNA (0.62) | RXRAPLA2G4BL3MBTL1LMNARXRB | |
| SCHEMBL13886146 | 0.79 | PLA2G4B (0.64) | PLA2G4BL3MBTL1LMNAKDM4ECYP1A2 | |
| SCHEMBL4325068 | 0.79 | PPARG (0.55) | PPARGRXRACYP3A4LMNAKDM4E | |
| SCHEMBL7905732 | 0.78 | PPARG (0.54) | PPARGRXRACYP3A4LMNAMAPT | |
| Oxalic Acid SCHEMBL5167729 | 0.78 | HPGD (0.57) | PPARGRXRACYP3A4L3MBTL1LMNA | |
| SCHEMBL7905734 | 0.78 | PPARG (0.54) | PPARGRXRACYP3A4LMNAMAPT | |
| SCHEMBL2007617 | 0.78 | FFAR1 (0.56) | PPARGRXRACYP3A4L3MBTL1LMNA | |
| SCHEMBL943621 | 0.78 | PPARG (0.56) | PPARGRXRACYP3A4L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006082495-A1 | PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | RANBAXY LABORATORIES LIMITED (IN) | 2006-08-10 | — | — | WO | claimed |
| WO-2006082495-A1 | PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | RANBAXY LABORATORIES LIMITED (IN) | 2006-08-10 | — | — | WO | disclosed |