SCHEMBL5822144

SCHEMBL5822144

CCCCCCCCCCCCCCCCOP(=O)(OCCCCCCCCCCCCCCCC)OCC[N+](C)(C)C

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.74
AKT1 P31749 2/20 0.74
ESR1 P03372 1/20 0.74
ADORA3 P0DMS8 1/20 0.74
CDC25A P30304 1/20 0.74
AGTR1 P30556 1/20 0.74
ADRA1A P35348 1/20 0.74
KCNH2 Q12809 1/20 0.74
CYP3A4 P08684 2/20 0.59
PRKD3 O94806 2/20 0.52
PRKCG P05129 2/20 0.52
PRKCB P05771 2/20 0.52
PRKCA P17252 2/20 0.52
PRKCH P24723 2/20 0.52
PRKCI P41743 2/20 0.52
PRKCE Q02156 2/20 0.52
PRKCQ Q04759 2/20 0.52
PRKCZ Q05513 2/20 0.52
PRKCD Q05655 2/20 0.52
PRKD1 Q15139 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22721395 1.00 LMNA (0.74) LMNAAKT1ESR1ADORA3CDC25A
SCHEMBL29060954 1.00 LMNA (0.74) LMNAAKT1ESR1ADORA3CDC25A
SCHEMBL27641196 0.95 LMNA (0.68) LMNAAKT1ESR1ADORA3CDC25A
SCHEMBL1933759 0.92 CYP3A4 (0.71) LMNAAKT1ESR1ADORA3CDC25A
SCHEMBL23016765 0.91 LMNA (0.68) LMNAAKT1ESR1ADORA3CDC25A
SCHEMBL19089460 0.91 LMNA (0.68) LMNAAKT1ESR1ADORA3CDC25A
SCHEMBL19089198 0.91 LMNA (0.68) LMNAAKT1ESR1ADORA3CDC25A
SCHEMBL18970789 0.91 LMNA (0.68) LMNAAKT1ESR1ADORA3CDC25A
SCHEMBL10325813 0.90 LMNA (0.62) LMNAAKT1ESR1ADORA3CDC25A
SCHEMBL29501185 0.88 CYP3A4 (0.76) LMNAAKT1ESR1ADORA3CDC25A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0248047-B1 MEDICAMENT WITH ANTI-TUMORAL ACTION CONTAINING HEXADECYLPHOSPHOCHOLINE Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 1991-06-19 EP claimed
WO-2006122716-A1 USE OF ETHER-LINKED LYSOPHOSPHATIDYLCHOLINES AND ALKYLPHOSPHOCHOLINES FOR THE TREATMENT OF PAPILLOMA VIRUS INDUCED WARTS AND SARCOIDS HEIDELBERG PHARMA GMBH (DE) 2006-11-23 WO disclosed
EP-0203093-B1 MONOCLONAL ANTIBODIES AGAINST ALVEOLAR SURFACTANT PROTEIN SCIOS NOVA INC. (US) 1993-08-04 EP disclosed
US-4656253-A Monoclonal antibodies against alveolar surfactant protein CALIFORNIA BIOTECHOLOGY, INC. (US) 1987-04-07 US disclosed
EP-0203093-A4 MONOCLONAL ANTIBODIES AGAINST ALVEOLAR SURFACTANT PROTEIN. CALIFORNIA BIOTECHNOLOGY INC (US) 1987-03-03 EP disclosed
EP-0203093-A1 MONOCLONAL ANTIBODIES AGAINST ALVEOLAR SURFACTANT PROTEIN. CALIFORNIA BIOTECHNOLOGY INC (US) 1986-12-03 EP disclosed
WO-1986002558-A1 MONOCLONAL ANTIBODIES AGAINST ALVEOLAR SURFACTANT PROTEIN CALIFORNIA BIOTECHNOLOGY, INC. (US) 1986-05-09 WO disclosed
US-4562003-A Monoclonal antibodies against alveolar surfactant protein CALIFORNIA BIOTECHNOLOGY, INC. (US) 1985-12-31 US disclosed