Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | RAB9A | P51151 | 5/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | BLM | P54132 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5824078 | 0.89 | MAPT (0.44) | MAPTRAB9ASMN1; SMN2NPC1LMNA | |
| SCHEMBL5821033 | 0.87 | MAPT (0.42) | MAPTRAB9ASMN1; SMN2NPC1KDM4E | |
| SCHEMBL5820244 | 0.86 | MAPT (0.49) | MAPTRAB9ASMN1; SMN2NPC1KDM4E | |
| SCHEMBL12113456 | 0.83 | ALDH1A1 (0.43) | MAPTRAB9ASMN1; SMN2NPC1KDM4E | |
| SCHEMBL1306853 | 0.83 | ALDH1A1 (0.43) | MAPTRAB9ASMN1; SMN2NPC1KDM4E | |
| SCHEMBL1306854 | 0.83 | ALDH1A1 (0.43) | MAPTRAB9ASMN1; SMN2NPC1KDM4E | |
| SCHEMBL5824269 | 0.81 | CGAS (0.39) | MAPTRAB9ASMN1; SMN2NPC1KDM4E | |
| Benzoic Acid SCHEMBL5808846 | 0.81 | TSHR (0.43) | MAPTRAB9ASMN1; SMN2NPC1KDM4E | |
| SCHEMBL1306293 | 0.80 | ALDH1A1 (0.46) | MAPTRAB9ASMN1; SMN2NPC1KDM4E | |
| SCHEMBL1306294 | 0.80 | ALDH1A1 (0.46) | MAPTRAB9ASMN1; SMN2NPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006025683-A1 | ARYLAMINOMETHYL PROPENYL BENZHYDROXYAMID DERIVATIVES WITH INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND METHOD FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2006-03-09 | — | — | WO | disclosed |