Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 15/20 | 0.73 |
| ▸ | KCNH2 | Q12809 | 8/20 | 0.73 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.73 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.70 |
| ▸ | HTR2C | P28335 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20528744 | 0.90 | CYP2D6 (0.77) | GHSRKCNH2CYP3A4CYP2D6HTR2C | |
| SCHEMBL20528746 | 0.90 | CYP2D6 (0.77) | GHSRKCNH2CYP3A4CYP2D6HTR2C | |
| SCHEMBL5791441 | 0.87 | GHSR (0.76) | GHSRKCNH2CYP3A4CYP2D6HTR2C | |
| SCHEMBL5809122 | 0.85 | GHSR (0.73) | GHSRKCNH2CYP3A4CYP2D6HTR2C | |
| SCHEMBL5791741 | 0.84 | GHSR (0.72) | GHSRKCNH2CYP3A4CYP2D6HTR2C | |
| SCHEMBL5793977 | 0.83 | GHSR (0.70) | GHSRKCNH2CYP3A4CYP2D6HTR2C | |
| SCHEMBL20528762 | 0.82 | CYP2D6 (1.00) | GHSRKCNH2CYP3A4CYP2D6 | |
| SCHEMBL5791862 | 0.82 | CYP2D6 (0.78) | GHSRKCNH2CYP3A4CYP2D6HTR2C | |
| SCHEMBL20528764 | 0.82 | CYP2D6 (1.00) | GHSRKCNH2CYP3A4CYP2D6 | |
| SCHEMBL21686465 | 0.79 | CYP2D6 (0.77) | GHSRKCNH2CYP3A4CYP2D6HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006012577-A2 | QUINAZOLINONE DERIVATIVES USEFUL FOR THE REGULATION OF GLUCOSE HOMEOSTASIS AND FOOD INTAKE | BAYER PHARMACEUTICALS CORPORATION (US) | 2006-02-02 | — | — | WO | disclosed |