Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 15/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 12/20 | 0.42 |
| ▸ | RET | P07949 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | AHR | P35869 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4393053 | 0.89 | ADORA2A (0.42) | ADORA2AADORA1ADORA3ADORA2BHPGD | |
| SCHEMBL5822970 | 0.84 | MAPT (0.48) | ADORA2AADORA1HPGDMAPTSMN1; SMN2 | |
| SCHEMBL3833076 | 0.83 | RET (0.37) | ADORA2AADORA1RETADORA3HPGD | |
| SCHEMBL5821098 | 0.83 | MAPK1 (0.41) | ADORA1RETADORA3HPGDMAPT | |
| SCHEMBL3833011 | 0.81 | MAPT (0.37) | RETNPC1MAPTRAB9A | |
| SCHEMBL5822946 | 0.81 | SMN1; SMN2 (0.38) | ADORA2AADORA1RETHPGDMAPT | |
| SCHEMBL4793494 | 0.80 | RET (0.36) | RETHPGDMAPTSMN1; SMN2 | |
| SCHEMBL3826198 | 0.79 | CNR1 (0.39) | RET | |
| SCHEMBL3833160 | 0.77 | RET (0.38) | RET | |
| SCHEMBL5822553 | 0.77 | PTK2 (0.38) | RETSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006124897-A2 | METHODS AND COMPOSITIONS FOR IMPROVING COGNITION | LEXICON GENETICS INCORPORATED (US) | 2006-11-23 | — | — | WO | disclosed |