SCHEMBL5822372 — predicted protein targets

Predicted protein targets (top 12)

	gene	UniProt	supporting neighbours	confidence
▸	RET	P07949	2/20	0.47

▸	PTK2	Q05397	2/20	0.44

▸	CSF1R	P07333	13/20	0.41

▸	KIT	P10721	2/20	0.39

▸	SRC	P12931	2/20	0.39

▸	FLT3	P36888	2/20	0.39

▸	INSR	P06213	1/20	0.39

▸	PDGFRB	P09619	1/20	0.39

▸	CAMK2D	Q13557	1/20	0.38

▸	AURKA	O14965	1/20	0.38

▸	STAT6	P42226	1/20	0.38

▸	NTRK1	P04629	1/20	0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL3820439	0.88	RET (0.47)	RETPTK2NTRK1
SCHEMBL27735796	0.84	PTK2 (0.41)	RETPTK2CSF1RCAMK2DAURKA
SCHEMBL5822504	0.83	TRPV1 (0.45)	RET
SCHEMBL3819845	0.80	NTRK1 (0.39)	RETPTK2NTRK1
SCHEMBL3823247	0.75	MAPT (0.45)	NTRK1
SCHEMBL3817641	0.74	DEGS1 (0.39)	RETAURKANTRK1
SCHEMBL3822155	0.74	RET (0.43)	RETNTRK1
SCHEMBL3820803	0.73	KMT2A (0.43)	RETKITNTRK1
SCHEMBL3820620	0.72	MAPT (0.42)	RETNTRK1
SCHEMBL3833160	0.71	RET (0.38)	RETPTK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2006124897-A2	METHODS AND COMPOSITIONS FOR IMPROVING COGNITION	LEXICON GENETICS INCORPORATED (US)	2006-11-23	—	—	WO	disclosed