Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
| ▸ | RET | P07949 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | JAK3 | P52333 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3823130 | 0.90 | TRPV1 (0.50) | TRPV1RETALDH1A1KDM4EUSP2 | |
| SCHEMBL5818418 | 0.88 | NAMPT (0.45) | ALDH1A1KDM4EHPGDHSD17B10USP2 | |
| SCHEMBL27714954 | 0.87 | KMT2A (0.47) | ALDH1A1KDM4EHPGDHSD17B10USP2 | |
| SCHEMBL4393164 | 0.83 | KMT2A (0.49) | TRPV1ALDH1A1HPGDUSP2MAPK1 | |
| SCHEMBL5822372 | 0.83 | RET (0.47) | RET | |
| SCHEMBL3821662 | 0.81 | KMT2A (0.58) | ALDH1A1KDM4EHPGDHSD17B10MAPK1 | |
| SCHEMBL3812216 | 0.79 | LMNA (0.50) | ALDH1A1HPGDUSP2MAPK1POLB | |
| SCHEMBL3818707 | 0.79 | ALDH1A1 (0.50) | ALDH1A1KDM4EHPGDHSD17B10POLB | |
| SCHEMBL3820495 | 0.77 | KMT2A (0.56) | TRPV1ALDH1A1KDM4EHPGDMAPK1 | |
| SCHEMBL3823614 | 0.77 | KMT2A (0.45) | ALDH1A1KDM4EHPGDHSD17B10POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006124897-A2 | METHODS AND COMPOSITIONS FOR IMPROVING COGNITION | LEXICON GENETICS INCORPORATED (US) | 2006-11-23 | — | — | WO | disclosed |