Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL10738326 | 0.95 | MAPT (0.44) | ALOX15MAPTRAB9APKMPPARA | |
| SCHEMBL1019370 | 0.79 | ALOX15 (0.50) | ALOX15RAB9APKMPPARACYP2C9 | |
| SCHEMBL8468005 | 0.78 | ALOX15 (0.48) | ALOX15RAB9APKMPPARACYP2C9 | |
| SCHEMBL3465226 | 0.76 | PPARA (0.47) | ALOX15MAPTRAB9APKMPPARA | |
| SCHEMBL11440739 | 0.72 | KCNA3 (0.46) | ALOX15PKMCYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL11529053 | 0.72 | ALOX15 (0.43) | ALOX15MAPTRAB9APKMPARP10 | |
| SCHEMBL11191140 | 0.72 | KCNA3 (0.50) | ALOX15RAB9APKMCYP2C9CYP2C19 | |
| SCHEMBL5724626 | 0.72 | PPARA (0.58) | ALOX15PPARACYP2C9 | |
| SCHEMBL7805112 | 0.70 | PPARA (0.49) | ALOX15MAPTRAB9APKMPPARA | |
| SCHEMBL8103778 | 0.70 | ALOX15 (0.48) | ALOX15PKMPPARACYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006058199-A1 | METHODS OF MODULATING HIGH-DENSITY LIPOPROTEIN CHOLESTEROL LEVELS AND PHARMACEUTICAL FORMULATIONS FOR THE SAME | FAZIX CORPORATION (US) | 2006-06-01 | — | — | WO | disclosed |
| US-20060111346-A1 | Methods of modulating high-density lipoprotein cholesterol levels and pharmaceutical formulations for the same | FAZIX CORPORATION. | 2006-05-25 | — | — | US | disclosed |
| US-4826861-A | MEDICAL BACTERICIDES OR FUNGICIDES | ALBERT ROLAND, S.A. (FR) | 1989-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060111346-A1 | Methods of modulating high-density lipoprotein cholesterol levels and pharmaceutical formulations for the same | HDLBP, LDLR, CETP | ALOX15 1739/4885MAPT 3110/4885RAB9A 3535/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.