Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 6/20 | 0.36 |
| ▸ | BACE1 | P56817 | 2/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | IDH1 | O75874 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1367988 | 0.87 | BACE1 (0.46) | DAOKMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL1367272 | 0.87 | BACE1 (0.46) | DAOKMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL1367270 | 0.87 | BACE1 (0.46) | DAOKMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL1366316 | 0.83 | DAO (0.46) | DAOKMT2AMAPTMEN1RAB9A | |
| SCHEMBL1368303 | 0.83 | DAO (0.46) | DAOKMT2AMAPTMEN1RAB9A | |
| SCHEMBL1366313 | 0.83 | DAO (0.46) | DAOKMT2AMAPTMEN1RAB9A | |
| SCHEMBL1369662 | 0.79 | DAO (0.40) | DAOALOX15BACE1 | |
| SCHEMBL1366903 | 0.79 | DAO (0.40) | DAOALOX15BACE1 | |
| SCHEMBL1366905 | 0.79 | DAO (0.40) | DAOALOX15BACE1 | |
| SCHEMBL1369702 | 0.78 | DAO (0.59) | DAOALOX15EGFRIDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006132947-A2 | 3-ACYL COUMARINS, THIOCHROMONES AND QUINOLONES AND THERAPEUTIC USES THEREOF | TEMPLE UNIVERSITY- OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2006-12-14 | — | — | WO | disclosed |