Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | KDM6B | O15054 | 1/20 | 0.49 |
| ▸ | KDM5C | P41229 | 1/20 | 0.49 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.49 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.49 |
| ▸ | JMJD6 | Q6NYC1 | 2/20 | 0.44 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.39 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.39 |
| ▸ | ERN1 | O75460 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SDHB | P21912 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.37 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.37 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL582140 | 0.93 | KDM4E (0.56) | KDM4CKDM4EKDM6BKDM5CKDM2A | |
| Hydrochloric Acid SCHEMBL581820 | 0.87 | KDM4C (0.52) | KDM4CKDM4EKDM6BKDM5CKDM2A | |
| Hydrochloric Acid SCHEMBL581941 | 0.82 | KDM4C (0.57) | KDM4CKDM4EKDM6BKDM5CKDM2A | |
| Hydrochloric Acid SCHEMBL582328 | 0.81 | KDM4E (0.48) | KDM4CKDM4EKDM6BKDM5CKDM2A | |
| SCHEMBL581845 | 0.80 | KDM4E (0.61) | KDM4CKDM4EKDM6BKDM5CKDM2A | |
| Hydrochloric Acid SCHEMBL581125 | 0.79 | KDM4E (0.46) | KDM4CKDM4EKDM6BKDM5CKDM2A | |
| Hydrochloric Acid SCHEMBL3089051 | 0.79 | KDM4E (0.60) | KDM4CKDM4EKDM6BKDM5CKDM2A | |
| SCHEMBL582158 | 0.79 | KDM4E (0.53) | KDM4CKDM4EKDM6BKDM5CKDM2A | |
| SCHEMBL390165 | 0.78 | KDM4E (0.60) | KDM4CKDM4EKDM6BKDM5CKDM2A | |
| SCHEMBL581107 | 0.78 | KDM4C (0.56) | KDM4CKDM4EKDM6BKDM5CKDM2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2417131-A1 | ISOXAZOL-3(2H)-ONE ANALOGS AS THERAPEUTIC AGENTS | AstraZeneca AB (SE) | 2012-02-15 | — | — | EP | disclosed |
| WO-2010117323-A1 | METHOD AND APPARATUS FOR PRODUCING HEAT ENERGY AND CARBON DIOXIDE | ASTRAZENECA AB (SE) | 2010-10-14 | — | — | WO | disclosed |