Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | KDM6B | O15054 | 1/20 | 0.60 |
| ▸ | KDM5C | P41229 | 1/20 | 0.60 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.60 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.60 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | ACLY | P53396 | 1/20 | 0.48 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.48 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.48 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31320054 | 0.85 | KDM4E (0.50) | KDM4EKDM6BKDM5CKDM4CKDM2A | |
| SCHEMBL14977130 | 0.82 | KDM4E (0.66) | KDM4EKDM6BKDM5CKDM4CKDM2A | |
| SCHEMBL13847864 | 0.81 | TAS1R3 (0.41) | KDM4EKDM6BKDM5CKDM4CKDM2A | |
| Hydrochloric Acid SCHEMBL581820 | 0.81 | KDM4C (0.52) | KDM4EKDM6BKDM5CKDM4CKDM2A | |
| SCHEMBL29894587 | 0.81 | KDM4E (0.86) | KDM4EKDM6BKDM5CKDM4CKDM2A | |
| SCHEMBL70279 | 0.81 | KDM4E (0.86) | KDM4EKDM6BKDM5CKDM4CKDM2A | |
| SCHEMBL4727956 | 0.81 | ATR (0.46) | KDM4EKDM6BKDM5CKDM4CKDM2A | |
| SCHEMBL27953096 | 0.81 | JMJD6 (0.56) | KDM4EKDM6BKDM5CKDM4CKDM2A | |
| SCHEMBL10339477 | 0.81 | TAS1R3 (0.51) | KDM4EKDM6BKDM5CKDM4CKDM2A | |
| Ethyl-2-Chloropyridine-4-Carboxylate SCHEMBL1425666 | 0.81 | JMJD6 (0.56) | KDM5CKDM4CL3MBTL1JMJD6NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 600 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118843616-A | Benzamide compounds for the treatment of bacterial infections | 豪夫迈·罗氏有限公司 | 2024-10-25 | — | — | CN | claimed |
| CN-118307822-B | Production process of environment-friendly laminating material | 广东美士达药包材料股份有限公司 | 2024-10-18 | — | — | CN | claimed |
| CN-118307822-A | Production process of environment-friendly laminating material | 广东美士达药包材料股份有限公司 | 2024-07-09 | — | — | CN | claimed |
| CN-112321494-B | Method for preparing 2-chloro-4-isopropylpyridine | 上海凌凯医药科技有限公司 | 2022-04-19 | — | — | CN | claimed |
| CN-112321494-A | Method for preparing 2-chloro-4-isopropylpyridine | 上海凌凯医药科技有限公司 | 2021-02-05 | — | — | CN | claimed |
| CN-103664766-B | Preparation method of 2-aminopyridine-4-methyl alcohol | UNIV ZHEJIANG | 2015-06-24 | — | — | CN | claimed |
| CN-103664766-A | Preparation method of 2-aminopyridine-4-methyl alcohol | UNIV ZHEJIANG | 2014-03-26 | — | — | CN | claimed |
| EP-4076459-B1 | PRMT5 INHIBITORS | MERCK SHARP & DOHME LLC (US) | 2026-04-29 | — | — | EP | disclosed |
| US-12595248-B2 | PRMT5 inhibitors | MERCK SHARP & DOHME LLC (US) | 2026-04-07 | — | — | US | disclosed |
| EP-4704830-A2 | MRGPRX2 INHIBITORS AND METHODS OF USE THEREOF | Septerna, Inc. (US) | 2026-03-11 | — | — | EP | disclosed |
| EP-4702025-A1 | BICYCLIC HETEROCYCLE COMPOUNDS FOR THE TREATMENT OF CANCER | F. Hoffmann-La Roche AG (CH) | 2026-03-04 | — | — | EP | disclosed |
| EP-4680607-A1 | BICYCLIC UREAS AS KINASE INHIBITORS | Incyte Corporation (US) | 2026-01-21 | — | — | EP | disclosed |
| EP-4076460-B1 | 1,4-DIHYDRO-2H-SPIRO[ISOQUINOLINE-3,4'-PIPERIDINE DERIVATIVES AS PRMT5 INHIBITORS FOR THE TREATMENT OF CANCER | MERCK SHARP & DOHME LLC (US) | 2026-01-21 | — | — | EP | disclosed |
| WO-1992020676-A1 | SUBSTITUTED 3-AMINOQUINUCLIDINES | PFIZER INC. (US) | 1992-11-26 | — | — | WO | disclosed |
| EP-0254856-B1 | PYRIDINETHANOL AMINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1991-09-04 | — | — | EP | disclosed |
| EP-0434132-A2 | Herbicidal acrylonitrile derivatives | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1991-06-26 | — | — | EP | disclosed |
| US-5010201-A | Process for the preparation of substituted 2-chloropyridines | BAYER AKTIENGESELLSCHAFT (DE) | 1991-04-23 | — | — | US | disclosed |
| US-4988714-A | Drugs for treatment of obesity and diabetics, increases protein breakdown, for fattening animals | HOFFMANN-LA ROCHE INC. (US) | 1991-01-29 | — | — | US | disclosed |
| US-4800206-A | ANTIDIABETIC AGENTS; HYPOGLYCEMIC AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1989-01-24 | — | — | US | disclosed |
| EP-0254856-A2 | Pyridinethanol amine derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1988-02-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12595248-B2 | PRMT5 inhibitors | PRMT5, PRMT1, PRMT6 | KDM4E 306/4885KDM6B 239/4885KDM5C 23/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.