Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14602904 | 0.83 | CRHR1 (0.30) | — | |
| SCHEMBL5624154 | 0.81 | — | — | |
| SCHEMBL5623907 | 0.80 | PDE2A (0.31) | — | |
| SCHEMBL5624150 | 0.80 | — | — | |
| SCHEMBL5623911 | 0.76 | — | — | |
| SCHEMBL19189722 | 0.74 | — | — | |
| SCHEMBL5627752 | 0.72 | CETP (0.37) | — | |
| SCHEMBL16124218 | 0.71 | CRHR1 (0.33) | — | |
| SCHEMBL16124231 | 0.68 | CRHR1 (0.34) | — | |
| SCHEMBL19189710 | 0.68 | CRHR1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1848430-A2 | NOVEL BENZYLAMINE DERIVATIVES AS CETP INHIBITORS | Reddy US Therapeutics, Inc. (US) | 2007-10-31 | — | — | EP | claimed |
| WO-2006073973-A2 | NOVEL BENZYLAMINE DERIVATIVES AS CETP INHIBITORS | REDDY US THERAPEUTICS, INC. (US) | 2006-07-13 | — | — | WO | claimed |