Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 13/20 | 0.75 |
| ▸ | CNR1 | P21554 | 7/20 | 0.75 |
| ▸ | UGCG | Q16739 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5822464 | 0.86 | CNR2 (0.85) | CNR2CNR1UGCG | |
| SCHEMBL5811776 | 0.86 | CNR2 (0.75) | CNR2CNR1EPHX2PTGS1PTGS2 | |
| SCHEMBL5806769 | 0.84 | CNR2 (0.96) | CNR2CNR1UGCG | |
| SCHEMBL5795556 | 0.82 | CNR2 (0.72) | CNR2CNR1CYP2C9GRIA2 | |
| SCHEMBL5795272 | 0.82 | CNR2 (0.69) | CNR2CNR1 | |
| SCHEMBL14003108 | 0.79 | CNR2 (0.71) | CNR2CNR1 | |
| SCHEMBL5808694 | 0.75 | CNR2 (0.68) | CNR2CNR1UGCGEPHX2 | |
| SCHEMBL5808093 | 0.75 | CNR2 (0.60) | CNR2CNR1 | |
| SCHEMBL5811963 | 0.72 | CNR2 (0.59) | CNR2CNR1 | |
| SCHEMBL13871396 | 0.72 | CNR2 (0.59) | CNR2CNR1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006030124-A1 | CONDENSED PYRAZOLE DERIVATIVES, PREPARATION METHOD THEREOF AND THERAPEUTIC USE OF SAME | SANOFI-AVENTIS (FR) | 2006-03-23 | — | — | WO | disclosed |