Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 3/20 | 0.40 |
| ▸ | CNR1 | P21554 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.36 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3571909 | 0.88 | ROCK2 (0.44) | F10CNR1LMNAALDH1A1L3MBTL1 | |
| SCHEMBL3573310 | 0.82 | UTS2R (0.41) | F10LMNAALDH1A1UTS2RROCK2 | |
| SCHEMBL3566288 | 0.80 | F10 (0.40) | F10CNR1LMNAALDH1A1ROCK2 | |
| SCHEMBL5823801 | 0.79 | F10 (0.38) | F10ALDH1A1SMN1; SMN2 | |
| SCHEMBL3558912 | 0.79 | F10 (0.45) | F10CNR1L3MBTL1UTS2RMAPT | |
| SCHEMBL3565027 | 0.78 | EP300 (0.48) | F10CNR1ALDH1A1UTS2RMAPT | |
| SCHEMBL3564096 | 0.78 | EP300 (0.48) | F10CNR1ALDH1A1UTS2RMAPT | |
| SCHEMBL3570136 | 0.78 | EP300 (0.48) | F10CNR1ALDH1A1UTS2RMAPT | |
| SCHEMBL3568353 | 0.78 | F10 (0.44) | F10CNR1UTS2RMAPT | |
| SCHEMBL3564018 | 0.77 | F10 (0.43) | F10CNR1UTS2RMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006063113-A2 | UREAS AS FACTOR XA INHIBITORS | PORTOLA PHARMACEUTICALS, INC. (US) | 2006-06-15 | — | — | WO | disclosed |