Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 4/20 | 0.49 |
| ▸ | FNTB | P49356 | 4/20 | 0.49 |
| ▸ | SYK | P43405 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3499680 | 0.91 | FNTA (0.58) | FNTAFNTBSYKPDE4BNAMPT | |
| SCHEMBL5823936 | 0.87 | FNTA (0.63) | FNTAFNTBACKR3 | |
| SCHEMBL3501261 | 0.81 | FNTA (0.57) | FNTAFNTBPOLBALDH1A1 | |
| SCHEMBL3499535 | 0.80 | FNTA (0.75) | FNTAFNTBALDH1A1KDM4EACKR3 | |
| SCHEMBL3501941 | 0.79 | FNTA (0.54) | FNTAFNTBPDE4BGAAHTT | |
| SCHEMBL3501587 | 0.78 | FNTA (0.59) | FNTAFNTBPOLBALDH1A1ACKR3 | |
| SCHEMBL3501149 | 0.78 | FNTA (0.75) | FNTAFNTBALDH1A1ACKR3 | |
| SCHEMBL3502196 | 0.77 | FNTA (0.60) | FNTAFNTBACKR3 | |
| SCHEMBL5824051 | 0.76 | ALDH1A1 (0.40) | FNTAFNTBALDH1A1 | |
| SCHEMBL3499170 | 0.76 | FNTA (0.61) | FNTAFNTBACKR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005089515-A2 | METHODS FOR THE TREATMENT OF SYNUCLEINOPATHIES | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2005-09-29 | — | — | WO | disclosed |
| EP-0892797-A4 | INHIBITORS OF FARNESYL PROTEIN TRANSFERASE | BRISTOL MYERS SQUIBB CO (US) | 2004-10-20 | — | — | EP | disclosed |
| EP-0892797-A1 | INHIBITORS OF FARNESYL PROTEIN TRANSFERASE | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-01-27 | — | — | EP | disclosed |
| WO-1997030992-A1 | INHIBITORS OF FARNESYL PROTEIN TRANSFERASE | BRISTOL-MYERS SQUIBB COMPANY (US) | 1997-08-28 | — | — | WO | disclosed |